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The genome sequence of the ethanologenic bacterium Zymomonas mobil is ZM4

Title
The genome sequence of the ethanologenic bacterium Zymomonas mobil is ZM4
Authors
Seo J.-S.Chong H.Park H.S.Yoon K.-O.Jung C.Kim J.J.Hong J.H.Kim H.Kim J.-H.Kil J.-I.Park C.J.Oh H.-M.Lee J.-S.Jin S.-J.Um H.-W.Lee H.-J.Oh S.-J.Kim J.Y.Kang H.L.Lee S.Y.Lee K.J.Kang H.S.
Ewha Authors
박현석
SCOPUS Author ID
박현석scopus
Issue Date
2005
Journal Title
Nature Biotechnology
ISSN
1087-0156JCR Link
Citation
vol. 23, no. 1, pp. 63 - 68
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
We report the complete genome sequence of Zymomonas mobilis ZM4 (ATCC31821), an ethanologenic microorganism of interest for the production of fuel ethanol. The genome consists of 2,056,416 base pairs forming a circular chromosome with 1,998 open reading frames (ORFs) and three ribosomal RNA transcription units. The genome lacks recognizable genes for 6-phosphofructokinase, an essential enzyme in the Embden-Meyerhof-Parnas pathway, and for two enzymes in the tricarboxylic acid cycle, the 2-oxoglutarate dehydrogenase complex and malate dehydrogenase, so glucose can be metabolized only by the Entner-Doudoroff pathway. Whole genome microarrays were used for genomic comparisons with the Z. mobilistype strain ZM1 (ATCC10988) revealing that 54 ORFs predicted to encode for transport and secretory proteins, transcriptional regulators and oxidoreductase in the ZM4 strain were absent from ZM1. Most of these ORFs were also found to be actively transcribed in association with ethanol production by ZM4.
DOI
10.1038/nbt1045
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엘텍공과대학 > 컴퓨터공학과 > Journal papers
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