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Early cysteine protease activity in excretory bladder triggers metacercaria excystment of Paragonimus westermani

Title
Early cysteine protease activity in excretory bladder triggers metacercaria excystment of Paragonimus westermani
Authors
Chung Y.B.Kim T.S.Yang H.J.
Ewha Authors
양현종
SCOPUS Author ID
양현종scopus
Issue Date
2005
Journal Title
Journal of Parasitology
ISSN
0022-3395JCR Link
Citation
Journal of Parasitology vol. 91, no. 4, pp. 953 - 954
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
The cysteine proteases of Paragonimus westermani metacercaria are known to initiate metacercaria excystment. However, their secretory sites, such as the intestine, tegument, and excretory bladder are not well defined. In this study, the metacercariae were labeled with bromodeoxyuridine (BrdU) to distinguish the initial activation sites. BrdU was labeled mainly at the excretory bladder and the excretory granules of the metacercariae and the newly excysted juvenile worms. This result shows that early 'defecation' of the proteases from the excretory bladder may accelerate the excystment of P. westermani metacercariae. © American Society of Parasitologists 2005.
DOI
10.1645/GE-475R.1
Appears in Collections:
의과대학 > 의학과 > Journal papers
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