View : 104 Download: 0

Diagnosis of small pulmonary lesions by transbronchial lung biopsy with radial endobronchial ultrasound and virtual bronchoscopic navigation versus CT-guided transthoracic needle biopsy: A systematic review and meta-analysis

Title
Diagnosis of small pulmonary lesions by transbronchial lung biopsy with radial endobronchial ultrasound and virtual bronchoscopic navigation versus CT-guided transthoracic needle biopsy: A systematic review and meta-analysis
Authors
Han, YejiKim, Hyun JungKong, Kyoung AeKim, Soo JungLee, Su HwanRyu, Yon JuLee, Jin HwaKim, YookyoungShim, Sung ShineChang, Jung Hyun
Ewha Authors
장중현이진화심성신
SCOPUS Author ID
장중현scopus; 이진화scopus; 심성신scopus
Issue Date
2018
Journal Title
PLOS ONE
ISSN
1932-6203JCR Link
Citation
vol. 13, no. 1
Publisher
PUBLIC LIBRARY SCIENCE
Indexed
SCIE; SCOPUS WOS
Abstract
Background Advances in bronchoscopy and CT-guided lung biopsy have improved the evaluation of small pulmonary lesions (PLs), leading to an increase in preoperative histological diagnosis. We aimed to evaluate the efficacy and safety of transbronchial lung biopsy using radial endobronchial ultrasound and virtual bronchoscopic navigation (TBLB-rEBUS& VBN) and CT-guided transthoracic needle biopsy (CT-TNB) for tissue diagnosis of small PLs. Methods A systematic search was performed in five electronic databases, including MEDLINE, EMBASE, Cochrane Library Central Register of Controlled Trials, Web of Science, and Scopus, for relevant studies in May 2016; the selected articles were assessed using meta-analysis. The articles were limited to those published after 2000 that studied small PLs <= 3 cm in diameter. Results From 7345 records, 9 articles on the bronchoscopic (BR) approach and 15 articles on the percutaneous (PC) approach were selected. The pooled diagnostic yield was 75% (95% confidence interval [CI], 69 +/- 80) using the BR approach and 93% (95% CI, 90 +/- 96) using the PC approach. For PLs <= 2 cm, the PC approach (pooled diagnostic yield: 92%, 95% CI: 88 +/- 95) was superior to the BR approach (66%, 95% CI: 55 +/- 76). However, for PLs > 2 cm but <= 3 cm, the diagnostic yield using the BR approach was improved to 81% (95% CI, 75 +/- 85). Complications of pneumothorax and hemorrhage were rare with the BR approach but common with the PC approach. Conclusions CT-TNB was superior to TBLB-rEBUS&VBN for the evaluation of small PLs. However, for lesions greater than 2 cm, the BR approach may be considered considering its diagnostic yield of over 80% and the low risk of procedure-related complications.
DOI
10.1371/journal.pone.0191590
Appears in Collections:
의과대학 > 의학과 > Journal papers
Files in This Item:
Diagnosis of small pulmonary lesions.pdf(2.05 MB)Download
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE