Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 신동해 | - |
dc.contributor.author | 김수원 | - |
dc.contributor.author | 김미선 | - |
dc.date.accessioned | 2018-02-08T16:31:19Z | - |
dc.date.available | 2018-02-08T16:31:19Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0887-3585 | - |
dc.identifier.issn | 1097-0134 | - |
dc.identifier.other | OAK-21841 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/239836 | - |
dc.description.abstract | The crystal structure of HldC from B. pseudomallei (BpHldC), the fourth enzyme of the heptose biosynthesis pathway, has been determined. BpHldC converts ATP and d-glycero--d-manno-heptose-1-phosphate into ADP-d-glycero--d-manno-heptose and pyrophosphate. The crystal structure of BpHldC belongs to the nucleotidyltransferase / phosphodiesterase superfamily sharing a common Rossmann-like / fold with a conserved T/HXGH sequence motif. The invariant catalytic key residues of BpHldC indicate that the core catalytic mechanism of BpHldC may be similar to that of other closest homologues. Intriguingly, a reorientation of the C-terminal helix seems to guide open and close states of the active site for the catalytic reaction. | - |
dc.language | English | - |
dc.publisher | WILEY | - |
dc.subject | heptose biosynthesis pathway | - |
dc.subject | HldC | - |
dc.subject | lipopolysaccharide | - |
dc.subject | melioidosis | - |
dc.subject | nucleotidyltransferase | - |
dc.title | Crystal structure of D-glycero-B-D-manno-heptose-1-phosphate adenylyltransferase from Burkholderia pseudomallei | - |
dc.type | Article | - |
dc.relation.issue | 1 | - |
dc.relation.volume | 86 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.startpage | 124 | - |
dc.relation.lastpage | 131 | - |
dc.relation.journaltitle | PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS | - |
dc.identifier.doi | 10.1002/prot.25398 | - |
dc.identifier.wosid | WOS:000418098300011 | - |
dc.identifier.scopusid | 2-s2.0-85033211829 | - |
dc.author.google | Park, Jimin | - |
dc.author.google | Kim, Hyojin | - |
dc.author.google | Kim, Suwon | - |
dc.author.google | Lee, Daeun | - |
dc.author.google | Kim, Mi-Sun | - |
dc.author.google | Shin, Dong Hae | - |
dc.contributor.scopusid | 신동해(57217374185) | - |
dc.contributor.scopusid | 김수원(57193241841) | - |
dc.contributor.scopusid | 김미선(57203466599;57195150819) | - |
dc.date.modifydate | 20230411112717 | - |