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Rosacea and its association with enteral microbiota in Korean females

Title
Rosacea and its association with enteral microbiota in Korean females
Authors
Nam, Jae-HuiYun, YeojunKim, Han-SaemKim, Han-NaJung, Ho JooChang, YoosooRyu, SeunghoShin, HocheolKim, Hyung-LaeKim, Won-Serk
Ewha Authors
김형래김한나윤여준
SCOPUS Author ID
김형래scopus; 김한나scopus; 윤여준scopusscopus
Issue Date
2018
Journal Title
EXPERIMENTAL DERMATOLOGY
ISSN
0906-6705JCR Link1600-0625JCR Link
Citation
vol. 27, no. 1, pp. 37 - 42
Keywords
gut microbiotametagenomerosacea
Publisher
WILEY
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Rosacea is a chronic inflammatory dermatosis affecting the face and eyes. An association between systemic comorbidities and rosacea has been reported, but the link to enteral microbiota is uncertain. We aimed to investigate the link between rosacea and enteral microbiota. A cross-sectional study was performed in a sample of Korean women who participated in a health check-up programme at the Kangbuk Samsung Hospital Health Screening Center between 23 June 2014 and 5 September 2014. The gut microbiome was evaluated by 16S rRNA gene and metagenome sequence analyses. A total of 12 rosacea patients and 251 controls were enrolled. We identified links between rosacea and several changes in gut microbiota: reduced abundance of Peptococcaceae family unknown genus, Methanobrevibacter (genus), Slackia (genus), Coprobacillus (genus), Citrobacter (genus), and Desulfovibrio (genus), and increased abundance of Acidaminococcus (genus), Megasphaera (genus), and Lactobacillales order unknown family unknown genus. A link between rosacea and enteral microbiota was observed in this metagenomic study. A large and elaborate study is needed to confirm these findings and to elucidate the mechanisms involved.
DOI
10.1111/exd.13398
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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