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Associations between fruits, vegetables, vitamin A, beta-carotene and flavonol dietary intake, and age-related macular degeneration in elderly women in Korea: the Fifth Korea National Health and Nutrition Examination Survey

Title
Associations between fruits, vegetables, vitamin A, beta-carotene and flavonol dietary intake, and age-related macular degeneration in elderly women in Korea: the Fifth Korea National Health and Nutrition Examination Survey
Authors
Kim, E-kKim, H.Kwon, O.Chang, N.
Ewha Authors
장남수권오란
SCOPUS Author ID
장남수scopus; 권오란scopus
Issue Date
2018
Journal Title
EUROPEAN JOURNAL OF CLINICAL NUTRITION
ISSN
0954-3007JCR Link1476-5640JCR Link
Citation
vol. 72, no. 1, pp. 161 - 167
Publisher
NATURE PUBLISHING GROUP
Indexed
SCI; SCIE; SCOPUS WOS
Abstract
BACKGROUND/OBJECTIVES: Age-related macular degeneration (AMD) is one of the principal causes of blindness. This study investigated the association between diet and the prevalence of AMD in elderly Korean women. SUBJECTS/METHODS: Study subjects were women aged >= 65 years (n = 1008) from the Korea National Health and Nutrition Examination Survey (2010-2012). The presence of early-and late-onset AMD was determined on the basis of a fundus photograph from a health examination survey. Food intake was estimated using 24 h recall. RESULTS: The prevalence of AMD was 18.8% in elderly women in Korea. Multiple logistic regression analysis showed a significant negative association between vegetable intake and AMD (odds ratio (OR) 0.44, 95% confidence interval (CI) 0.25, 0.77, P for trend = 0.002) after adjusting for age, body mass index, postmenopausal period, duration of hormone replacement therapy, residential area, education level, family income, smoking status, alcohol consumption, dietary supplement use and total energy intake. After adjusting for potential confounders, the ORs between extreme quartiles were 0.55 (95% CI 0.29, 1.05, P for trend = 0.070) for fruit and vegetable intake, 0.38 (95% CI 0.21, 0.68, P for trend = 0.001) for vitamin A, 0.36 (95% CI 0.19, 0.67, P for trend < 0.001) for beta-carotene and 0.45 (95% CI 0.25, 0.82, P for trend = 0.008) for flavonols. CONCLUSIONS: These results suggest that higher consumption of fruits and vegetables containing antioxidant nutrients and phytochemicals may provide some protection against AMD.
DOI
10.1038/ejcn.2017.152
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신산업융합대학 > 식품영양학과 > Journal papers
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