Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 문창모 | * |
dc.date.accessioned | 2018-01-11T16:30:44Z | - |
dc.date.available | 2018-01-11T16:30:44Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 0815-9319 | * |
dc.identifier.issn | 1440-1746 | * |
dc.identifier.other | OAK-21438 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/239722 | - |
dc.description.abstract | Background and Aim: The role of screening or diagnostic colonoscopy to detect advanced neoplasia in young cohorts of age < 50 is unclear. This study compared the risk of colorectal neoplasia in a young age cohort against that in 50-54s screening cohort. Methods: A multi-center retrospective study was conducted at 14 university hospitals to compare the detection rates of neoplasia and advanced neoplasia in screening or diagnostic colonoscopy in the young cohort of < 50s against those in screening colonoscopy in the 50-54s cohort. Results: Among 10 477 eligible subjects, 9765 subjects were enrolled after excluding 712 subjects. Advanced neoplasia detection rates in the young screening cohort was significantly lower than that in the 50-54s screening cohort (5.9% vs 9.3%, P < 0.001). Compared with 50-54s screening cohort, the risk of advanced neoplasia was significantly reduced by 23%, 53%, and 54% in the 45-49s, 40-44s, and 20-39s screening cohorts, respectively. The detection rates of advanced neoplasia in the young diagnostic cohort was 5.0%, which was much lower than 11.8% in 50-54s screening cohort (P < 0.001). Compared with the 50-54s screening cohort, the risk of advanced neoplasia was significantly reduced by 50%, 66%, and 71% in the 45-49s, 40-44s, and 20-39s diagnostic cohorts, respectively. Conclusions: Colonoscopy to detect advanced neoplasia in young adults aged < 50 years should be reconsidered as their risk of advanced neoplasia on screening or diagnostic colonoscopy was much lower than those of 50-54s screening cohort; however, colonoscopy screening may be justified for high-risk 45-49s cohorts. | * |
dc.language | English | * |
dc.publisher | WILEY | * |
dc.subject | colonoscopy | * |
dc.subject | colorectal neoplasm | * |
dc.subject | screening | * |
dc.subject | young adults | * |
dc.title | Risks of colorectal advanced neoplasia in young adults versus those of screening colonoscopy in patients aged 50 to 54 years | * |
dc.type | Article | * |
dc.relation.issue | 11 | * |
dc.relation.volume | 32 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 1825 | * |
dc.relation.lastpage | 1831 | * |
dc.relation.journaltitle | JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY | * |
dc.identifier.doi | 10.1111/jgh.13798 | * |
dc.identifier.wosid | WOS:000417445600010 | * |
dc.identifier.scopusid | 2-s2.0-85030791234 | * |
dc.author.google | Kim, Kyeong Ok | * |
dc.author.google | Yang, Hyo-Joon | * |
dc.author.google | Cha, Jae Myung | * |
dc.author.google | Shin, Jeong Eun | * |
dc.author.google | Kim, Hyun Gun | * |
dc.author.google | Cho, Young-Seok | * |
dc.author.google | Boo, Sun-Jin | * |
dc.author.google | Lee, Jun | * |
dc.author.google | Jung, Yunho | * |
dc.author.google | Lee, Hyun Jung | * |
dc.author.google | Huh, Kyu Chan | * |
dc.author.google | Joo, Young-Eun | * |
dc.author.google | Park, Jongha | * |
dc.author.google | Moon, Chang Mo | * |
dc.contributor.scopusid | 문창모(8131765500) | * |
dc.date.modifydate | 20240222123305 | * |