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Multiplexed photoluminescent sensors: Towards improved disease diagnostics
- Multiplexed photoluminescent sensors: Towards improved disease diagnostics
- He X.-P.; Hu X.-L.; James T.D.; Yoon J.; Tian H.
- Ewha Authors
- SCOPUS Author ID
- Issue Date
- Journal Title
- Chemical Society Reviews
- vol. 46, no. 22, pp. 6687 - 6696
- Royal Society of Chemistry
- SCI; SCIE; SCOPUS
- The ability to simultaneously monitor multiple analytes in, for example, a single microplate well, is important for both basic research and clinical applications. In particular, for disease diagnosis there is a growing awareness that determination of a single disease biomarker is insufficient to pathologically confirm a disease state. Consequently, much recent literature has been directed towards the development of multiplexed photoluminescent sensors which can simultaneously detect multiple and diverse biomarkers that exist in a homogenous solution or a single cell, accelerating the progress towards precise disease diagnosis. This tutorial review highlights a selection of recent contributions towards this emerging interdisciplinary field that incorporates chemistry, chemical biology, materials sciences and medical sciences. © 2017 The Royal Society of Chemistry.
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