Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 송태진 | * |
dc.date.accessioned | 2017-11-01T05:01:57Z | - |
dc.date.available | 2017-11-01T05:01:57Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 0021-9150 | * |
dc.identifier.other | OAK-21147 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/239066 | - |
dc.description.abstract | Background and aims Although stroke patients have a high risk of ischemic heart disease, little information is available on the risk of coronary events in stroke patients with asymptomatic coronary artery disease (CAD). We investigated the long-term vascular outcomes in stroke patients with asymptomatic CAD diagnosed with multi-detector coronary computed tomography (MDCT). Methods This study was a retrospective analysis using a prospective cohort of ischemic stroke patients. We included consecutive stroke patients without history or symptoms of CAD who underwent MDCT. We investigated the long-term risk of major adverse cardiovascular events (MACE: cardiovascular mortality, ischemic stroke, myocardial infarction, unstable angina, and urgent coronary revascularization) and composite of MACE/all-cause mortality/elective coronary revascularization. We further investigated the value of MDCT for MACE prediction. Results Among the 1893 included patients, 1349 (71.3%) patients had some degree of CAD and 654 patients (34.5%) had significant (≥50%) CAD. At follow-up (median, 4.4 years), MACE occurred in 230 patients (12.2%). Event rates of MACE increased with the increasing extent of CAD. After adjustment for age, sex, and risk factors, the hazard ratios for MACE in mild CAD, 1-VD, 2-VD, and 3-VD or left main coronary disease were 1.28 (95% confidence interval [CI]: 0.88–1.87), 1.39 (95% CI: 0.90–2.16), 2.22 (95% CI: 1.39–3.55), and 2.91 (95% CI: 1.82–4.65), respectively (no CAD as a reference). Diagnosis of asymptomatic CAD significantly improved the prediction of MACE. Conclusions Asymptomatic CAD detected on MDCT was associated with increased risks of vascular events or deaths in acute stroke patients. © 2017 Elsevier B.V. | * |
dc.language | English | * |
dc.publisher | Elsevier Ireland Ltd | * |
dc.subject | Coronary artery disease | * |
dc.subject | Ischemic stroke | * |
dc.subject | Major adverse cardiac event | * |
dc.subject | Mortality | * |
dc.subject | Multidetector computerized tomography | * |
dc.title | Poor long-term outcomes in stroke patients with asymptomatic coronary artery disease in heart CT | * |
dc.type | Article | * |
dc.relation.volume | 265 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 7 | * |
dc.relation.lastpage | 13 | * |
dc.relation.journaltitle | Atherosclerosis | * |
dc.identifier.doi | 10.1016/j.atherosclerosis.2017.07.029 | * |
dc.identifier.wosid | WOS:000411436900002 | * |
dc.identifier.scopusid | 2-s2.0-85027570633 | * |
dc.author.google | Yoo J. | * |
dc.author.google | Song D. | * |
dc.author.google | Baek J.-H. | * |
dc.author.google | Kim K. | * |
dc.author.google | Kim J. | * |
dc.author.google | Song T.-J. | * |
dc.author.google | Lee H.S. | * |
dc.author.google | Choi D. | * |
dc.author.google | Kim Y.D. | * |
dc.author.google | Nam H.S. | * |
dc.author.google | Heo J.H. | * |
dc.contributor.scopusid | 송태진(55507164200) | * |
dc.date.modifydate | 20240304123954 | * |