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dc.contributor.author전상범*
dc.date.accessioned2017-11-01T05:01:57Z-
dc.date.available2017-11-01T05:01:57Z-
dc.date.issued2017*
dc.identifier.issn0304-3940*
dc.identifier.otherOAK-21146*
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/239065-
dc.description.abstractHearing loss in mature ears can cause functional reorganization of the auditory cortex. The functional reorganization is speculated to negatively affect the outcome of hearing rehabilitation. Therefore, once hearing loss occurs, it is important to provide auditory input before extensive reorganization in the auditory pathways. We investigated the neural plasticity in auditory cortex after single-sided deafness (SSD) in an adult rat model. The animals were divided into two groups: a normal hearing (NH) and the SSD group. The neural recordings of the SSD group were conducted at different time points (2, 4, 6 and 8 weeks) after cochlear ablation. The multi-unit activity was discriminated on the sum of spikes, peak amplitude, onset latency, peak latency, and responsive area based on the peak amplitude. The auditory cortical reorganization was observed after SSD. The contralateral dominance of peak amplitude and latency that normally occur in NH group were not present in the SSD group, replaced by higher amplitude and faster response in ipsilateral cortex. According to serial recordings at different time points after SSD, different phases in the response of the auditory cortex were speculated. Compared with normal hearing, alteration of contralateral dominance was observed because of the functional reorganization of the auditory cortex after SSD. © 2017 Elsevier B.V.*
dc.languageEnglish*
dc.publisherElsevier Ireland Ltd*
dc.subjectAuditory cortex*
dc.subjectContralateral dominance*
dc.subjectFunctional reorganization*
dc.subjectSingle-sided deafness*
dc.titleDisappearance of contralateral dominant neural activity of auditory cortex after single-sided deafness in adult rats*
dc.typeArticle*
dc.relation.volume657*
dc.relation.indexSCIE*
dc.relation.indexSCOPUS*
dc.relation.startpage171*
dc.relation.lastpage178*
dc.relation.journaltitleNeuroscience Letters*
dc.identifier.doi10.1016/j.neulet.2017.08.001*
dc.identifier.wosidWOS:000411849000028*
dc.identifier.scopusid2-s2.0-85027567000*
dc.author.googleLee M.Y.*
dc.author.googleKim D.H.*
dc.author.googlePark S.-K.*
dc.author.googleJun S.B.*
dc.author.googleLee Y.*
dc.author.googleChoi J.-J.*
dc.author.googleYoo H.J.*
dc.author.googleRaphael Y.*
dc.author.googleOh S.-H.*
dc.contributor.scopusid전상범(15843339100)*
dc.date.modifydate20240322125603*
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공과대학 > 전자전기공학전공 > Journal papers
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