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Effect of health literacy on adherence to osteoporosis treatment among patients with distal radius fracture

Title
Effect of health literacy on adherence to osteoporosis treatment among patients with distal radius fracture
Authors
Roh Y.H.Koh Y.D.Noh J.H.Gong H.S.Baek G.H.
Ewha Authors
고영도노영학
SCOPUS Author ID
고영도scopus; 노영학scopus
Issue Date
2017
Journal Title
Archives of Osteoporosis
ISSN
1862-3522JCR Link
Citation
vol. 12, no. 1
Keywords
AdherenceBisphophonatesDistal radius fractureHealth literacyOsteoporosis treatment
Publisher
Springer London
Indexed
SCIE; SCOPUS WOS scopus
Abstract
Summary: Patients with inadequate health literacy, those with medical comorbidities, or those with a previous history of adverse drug events have a higher likelihood of non-adherence to osteoporosis treatment after sustaining a distal radius fracture. Introduction: Patients with a distal radial fracture (DRF) have a higher risk of subsequent fractures, which provides an important opportunity to begin treatment for osteoporosis. This study assessed the effect that health literacy of patients suffering from a DRF has on the subsequent adherence to osteoporosis treatment. Methods: A total of 116 patients (female, over 50 years of age) presenting a DRF caused by low-energy trauma were enrolled. Their health literacy was measured using the Newest Vital Sign (NVS). Alendronate (70 mg, orally, once weekly) was prescribed to all patients for 1 year, and adherence was defined as taking at least 80% of the tablets for 12 months and returning for the visit on month 12. Multivariable analyses were conducted to determine whether the patients’ clinical, demographic, and health literacy factors influenced their adherence to osteoporosis treatment. Results: About half (52%) of the participants who sustained a DRF exhibited an inadequate health literacy, and the rate of non-adherence to osteoporosis treatment was 38%. The rate of non-adherence for patients with inadequate literacy was significantly higher than for those with appropriate literacy (47 vs. 29%, p = 0.04). The results of the regression analysis indicate that limited health literacy, the presence of comorbidities, and prior history of adverse drug events are associated with a higher likelihood of non-adherence to osteoporosis treatment after sustaining a DRF. Conclusions: Patients with inadequate health literacy, adverse drug events, or medical comorbidities had higher rates of non-adherence with alendronate treatment after sustaining a DRF. Further research is needed to show whether improvements in patient comprehension via informational intervention in patients with a DRF will improve adherence to osteoporosis treatment. © 2017, International Osteoporosis Foundation and National Osteoporosis Foundation.
DOI
10.1007/s11657-017-0337-0
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의과대학 > 의학과 > Journal papers
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