View : 22 Download: 0

Molecular Neuroimaging in Posttraumatic Stress Disorder

Title
Molecular Neuroimaging in Posttraumatic Stress Disorder
Authors
Im, Jooyeon JamieNamgung, EunChoi, YejeeKim, Jung YoonRhie, Sandy JeongYoon, Sujung
Ewha Authors
윤수정
SCOPUS Author ID
윤수정scopus
Issue Date
2016
Journal Title
EXPERIMENTAL NEUROBIOLOGY
ISSN
1226-2560JCR Link2093-8144JCR Link
Citation
vol. 25, no. 6, pp. 277 - 295
Keywords
Posttraumatic stress disorder (PTSD)Molecular neuroimagingPositron emission tomography (PET)Single photon emission computed tomography (SPECT)Magnetic resonance spectroscopy (MRS)
Publisher
KOREAN SOC BRAIN & NEURAL SCIENCE, KOREAN SOC NEURODEGENERATIVE DISEASE
Indexed
KCI WOS
Abstract
Over the past decade, an increasing number of neuroimaging studies have provided insight into the neurobiological mechanisms of posttraumatic stress disorder (PSTD). In particular, molecular neuroimaging techniques have been employed in examining metabolic and neurochemical processes in PTSD. This article reviews molecular neuroimaging studies in PTSD and focuses on findings using three imaging modalities including positron emission tomography (PET), single photon emission computed tomography (SPECT), and magnetic resonance spectroscopy (MRS). Although there were some inconsistences in the findings, patients with PTSD showed altered cerebral metabolism and perfusion, receptor bindings, and metabolite profiles in the limbic regions, medial prefrontal cortex, and temporal cortex. Studies that have investigated brain correlates of treatment response are also reviewed. Lastly, the limitations of the molecular neuroimaging studies and potential future research directions are discussed.
DOI
10.5607/en.2016.25.6.277
Appears in Collections:
연구기관 > 뇌융합과학연구원 > Journal papers
Files in This Item:
There are no files associated with this item.


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE