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Ascending aortic diameter is associated with hypertension in Korean men

Title
Ascending aortic diameter is associated with hypertension in Korean men
Authors
Suh, EunkyungRyoo, Jae-HongMiae-DooLee, Hong SooLee, Sang WhaShim, Kyung WonLee, Ju YoungByun, A. RiChun, Hyejin
Ewha Authors
이상화이홍수
SCOPUS Author ID
이상화scopus; 이홍수scopus
Issue Date
2017
Journal Title
CLINICAL AND INVESTIGATIVE MEDICINE
ISSN
0147-958XJCR Link1488-2353JCR Link
Citation
vol. 40, no. 4, pp. E158 - E166
Publisher
CANADIAN SOC CLINICAL INVESTIGATION
Indexed
SCI; SCIE; SCOPUS WOS
Abstract
Purpose: The purpose of this study was to evaluate the association between ascending aortic diameter (AAD) as measured with low-dose chest computed tomography (LDCT) and hypertension in Korean men. Methods: Korean men (n=1,050) who were screened for lung cancer using LDCT imaging at a health promotion center in Seoul, Korea between January 1 and December 31 were recruited for the study. AAD is the longest length of ascending aorta measured from approximately 15 mm above left main coronary ostium to the mid-slice level of the right pulmonary artery. Results: AAD were divided into quartiles, and the degree of hypertension was determined based on the quartiles of the AAD using logistic regression. Odds ratios (OR) for the proportion of hypertension in Q2 (1.70, 95% CI: 1.11-2.59), Q3 (2.72, 95% CI: 1.81-4.09) and Q4 (3.94, 95% CI: 2.63-5.89) were significantly greater than that of Q1 (P for trend < 0.001). Even after controlling for confounding covariates of age, BMI, total cholesterol, HDL-cholesterol, fasting glucose, GGT, ALT, eGFR, smoking status and alcohol intake, there was significant correlation. Conclusion: AAD was significantly associated with the degree of hypertension.
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의학전문대학원 > 의학과 > Journal papers
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