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The pattern of choosing dialysis modality and related mortality outcomes in Korea: A national population-based study

Title
The pattern of choosing dialysis modality and related mortality outcomes in Korea: A national population-based study
Authors
Kim H.J.Park J.T.Han S.H.Yoo T.-H.Park H.-C.Kang S.-W.Kim K.H.Ryu D.-R.Kim H.
Ewha Authors
류동열
SCOPUS Author ID
류동열scopus
Issue Date
2017
Journal Title
Korean Journal of Internal Medicine
ISSN
1226-3303JCR Link
Citation
vol. 32, no. 4, pp. 699 - 710
Keywords
ComorbidityMortalityPeritoneal dialysisRenal dialysis
Publisher
Korean Association of Internal Medicine
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
Background/Aims: Since comorbidities are major determinants of modality choice, and also interact with dialysis modality on mortality outcomes, we examined the pattern of modality choice according to comorbidities and then evaluated how such choices affected mortality in incident dialysis patients. Methods: We analyzed 32,280 incident dialysis patients in Korea. Patterns in initial dialysis choice were assessed by multivariate logistic regression analyses. Multivariate Poisson regression analyses were performed to evaluate the effects of interactions between comorbidities and dialysis modality on mortality and to quantify these interactions using the synergy factor. Results: Prior histories of myocardial infarction (p = 0.031), diabetes (p = 0.001), and congestive heart failure (p = 0.003) were independent factors favoring the initiation with peritoneal dialysis (PD), but were associated with increased mortality with PD. In contrast, a history of cerebrovascular disease and 1-year increase in age favored initiation with hemodialysis (HD) and were related to a survival benefit with HD (p < 0.001, both). While favoring initiation with HD, having Medical Aid (p = 0.001) and male gender (p = 0.047) were related to increased mortality with HD. Furthermore, although the severity of comorbidities did not inf luence dialysis modality choice, mortality in incident PD patients was significantly higher compared to that in HD patients as the severity of comorbidities increased (p for trend < 0.001). Conclusions: Some comorbidities exerted independent effects on initial choice of dialysis modality, but this choice did not always lead to the best results. Further analyses of the pattern of choosing dialysis modality according to baseline comorbid conditions and related consequent mortality outcomes are needed. © 2017 The Korean Association of Internal Medicine.
DOI
10.3904/kjim.2017.141
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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