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Blood Pressure Control During Chronic Kidney Disease Progression

Title
Blood Pressure Control During Chronic Kidney Disease Progression
Authors
Lee, SeulbiOh, Hyung JungLee, Eun-KyungLee, OesookHa, EunheeKim, Seung-JungKang, Duk-HeeChoi, Kyu BokRyu, Dong-Ryeol
Ewha Authors
류동열이은경오형중
SCOPUS Author ID
류동열scopus; 이은경scopus; 오형중scopus
Issue Date
2017
Journal Title
AMERICAN JOURNAL OF HYPERTENSION
ISSN
0895-7061JCR Link1941-7225JCR Link
Citation
vol. 30, no. 6, pp. 610 - 616
Keywords
blood pressurechronic kidney diseasehypertensionpulse pressure
Publisher
OXFORD UNIV PRESS
Indexed
SCI; SCIE; SCOPUS WOS
Abstract
BACKGROUND Hypertension is a major cause of end-stage renal disease, and blood pressure (BP)control is crucial in patients with chronic kidney disease (CKD). However, it is generally inadequately controlled in CKD patients. We investigated the prevalence of CKD patients with inadequate BP control and its related factors, based on the CKD stage. METHODS We analyzed the health examination sample cohort database, which consisted of the randomly selected participants among all the citizens who received the health examination provided by National Health Insurance Service of Korea in 2012 and 2013. RESULTS There were 27,350 CKD patients (7.9%) out of a total of 345,044 participants. As CKD stage progressed, there were more patients with poorly controlled hypertension compared to those with well-controlled hypertension. In addition, systolic BP increased with CKD stage progression, while diastolic BP was not significantly different. Age, female, body mass index, increased pulse pressure, CKD stage, and levels of fasting glucose, total cholesterol, hemoglobin, and proteinuria were significant factors associated with poor control of BP in hypertensive CKD patients. CONCLUSION The proportion of CKD patients with poorly controlled hypertension significantly increased as CKD progressed, mainly associated with the increase in pulse pressure. However, future investigation for causal relationship between poorly controlled hypertension and its related factors is needed.
DOI
10.1093/ajh/hpx017
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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