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A two-photon fluorescent probe for specific detection of hydrogen sulfide based on a familiar ESIPT fluorophore bearing AIE characteristics

Title
A two-photon fluorescent probe for specific detection of hydrogen sulfide based on a familiar ESIPT fluorophore bearing AIE characteristics
Authors
Chen, LiyanWu, DiLim, Chang SuKim, DayoungNam, Sang-JipLee, WoolinKim, GyungmiKim, Hwan MyungYoon, Juyoung
Ewha Authors
윤주영
SCOPUS Author ID
윤주영scopus
Issue Date
2017
Journal Title
CHEMICAL COMMUNICATIONS
ISSN
1359-7345JCR Link1364-548XJCR Link
Citation
vol. 53, no. 35, pp. 4791 - 4794
Publisher
ROYAL SOC CHEMISTRY
Indexed
SCI; SCIE; SCOPUS WOS
Abstract
Hydrogen sulfide (H2S) is a signaling gasotransmitter, which plays various roles in modulating the functions of different systems. In this study, a "turn-on'' fluorescent probe for H2S was developed. The probe, whose design is based on a familiar excited state intramolecular proton transfer (ESIPT) fluorophore bearing aggregation-induced emission (AIE) characteristics, was found to exhibit an 80-fold fluorescence enhancement along with a large Stokes shift upon the addition of H2S. Furthermore, the probe was successfully utilized to detect H2S in HeLa cells with both one-photon and two-photon microscopy.
DOI
10.1039/c7cc01695f
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
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