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Effects of metabolic syndrome on the functional outcomes of corticosteroid injection for de Quervain tenosynovitis

Title
Effects of metabolic syndrome on the functional outcomes of corticosteroid injection for de Quervain tenosynovitis
Authors
Roh Y.H.Noh J.H.Gong H.S.Baek G.H.
Ewha Authors
노영학
SCOPUS Author ID
노영학scopus
Issue Date
2017
Journal Title
Journal of Hand Surgery: European Volume
ISSN
1753-1934JCR Link
Citation
vol. 42, no. 5, pp. 481 - 486
Keywords
corticosteroid injectionDe Quervain tenosynovitismetabolic syndrome
Publisher
SAGE Publications Ltd
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Metabolic syndrome is a constellation of medical conditions that arise from insulin resistance and abnormal adipose deposition and function. In patients with metabolic syndrome and De Quervain tenosynovitis this might affect the outcome of treatment by local corticosteroid injection. A total of 64 consecutive patients with De Quervain tenosynovitis and metabolic syndrome treated with corticosteroid injection were age- and sex-matched with 64 control patients without metabolic syndrome. The response to treatment, including visual analogue scale score for pain, objective findings consistent with De Quervain tenosynovitis (tenderness at first dorsal compartment, Finkelstein test result), and Disability of the Arm, Shoulder, and Hand score were assessed at 6, 12, and 24 weeks follow-up. Treatment failure was defined as persistence of symptoms or surgical intervention. Prior to treatment, patients with metabolic syndrome had mean initial pain visual analogue scale and Disability of the Arm, Shoulder, and Hand scores similar to those in the control group. The proportion of treatment failure in the metabolic syndrome group (43%) was significantly higher than that in the control group (20%) at 6 months follow-up. The pain visual analogue scale scores in the metabolic syndrome group were higher than the scores in the control group at the 12- and 24-week follow-ups. The Disability of the Arm, Shoulder, and Hand scores of the metabolic syndrome group were higher (more severe symptoms) than those of the control group at the 12- and 24-week follow-ups. Although considerable improvements in symptom severity and hand function will likely occur in patients with metabolic syndrome, corticosteroid injection for De Quervain tenosynovitis is not as effective in these patients compared with age- and sex-matched controls in terms of functional outcomes and treatment failure. Level of evidence: III. © The Author(s) 2015.
DOI
10.1177/1753193417694112
Appears in Collections:
의과대학 > 의학과 > Journal papers
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