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Point prevalence and epidemiological characteristics of chronic cough in the general adult population The Korean National Health and Nutrition Examination Survey 2010-2012

Title
Point prevalence and epidemiological characteristics of chronic cough in the general adult population The Korean National Health and Nutrition Examination Survey 2010-2012
Authors
Kang, Min-GyuSong, Woo-JungKim, Hyun-JungWon, Ha-KyeongSohn, Kyoung-HeeKang, Sung-YoonJo, Eun-JungKim, Min-HyeKim, Sae-HoonKim, Sang-HeonPark, Heung-WooChang, Yoon-SeokLee, Byung-JaeMorice, Alyn H.Cho, Sang-Heon
Ewha Authors
김민혜
SCOPUS Author ID
김민혜scopus
Issue Date
2017
Journal Title
MEDICINE
ISSN
0025-7974JCR Link1536-5964JCR Link
Citation
vol. 96, no. 13
Keywords
adultchronic coughepidemiologypoint prevalence
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Indexed
SCI; SCIE; SCOPUS WOS
Abstract
Cough is frequently self-limiting, but may persist longer in certain individuals.Most of previous studies on the epidemiology of chronic cough have only measured period prevalence, and thus have afforded limited information on the burden and natural course.We aimed to investigate the epidemiology of chronic cough by using a point prevalence measure in a large-scale general population. We analyzed cross-sectional data collected from 18,071 adults who participated in the Korean National Health and Nutrition Examination Survey 2010-2012.Presence and duration of current cough was ascertained by structured questionnaires, and cough was classified into acute (<3 weeks), subacute (3-8 weeks), or chronic cough (>= 8 weeks).Demographic and clinical parameters were examined in relation to chronic cough. The point prevalences of acute, subacute, and chronic cough were 2.5+/-0.2%, 0.8+/-0.1% and 2.6+/-0.2%, respectively.The proportion of current cough showed a steep decrease after 1 week of duration.However, 2 peaks in the prevalence of current cough were revealed; cough durations of less than 1 week and longer than 1 year were most common (31.1% and 27.7% of current cough, respectively).Subacute and chronic cough were more prevalent in the elderly (>= 65 years); the positive associations with older age were independent of other confounders, including current smoking and comorbidities. This is the first report on the epidemiology of cough using a point prevalence measure in a nationally representative population sample.Our findings indicate a high burden of chronic cough among adults with current cough in the community.The dual-peak of cough duration suggested that the pathophysiology of acute and chronic cough may differ.The preponderance of elderly people in the prevalence of chronic cough warrants further investigation.In addition, more sophistication and validation of tools to define chronic cough will help our understanding of the epidemiology.
DOI
10.1097/MD.0000000000006486
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의료원 > 의료원 > Journal papers
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