Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김혜순 | * |
dc.contributor.author | 공경애 | * |
dc.date.accessioned | 2017-03-16T01:03:47Z | - |
dc.date.available | 2017-03-16T01:03:47Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 1738-1061 | * |
dc.identifier.other | OAK-20273 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/234770 | - |
dc.description.abstract | Purpose: Serum level of 25-hydroxyvitamin D (25-OHD) is considered as the most appropriate marker of vitamin D status. However, only a few studies have investigated the relationship between 25-OHD and parathyroid hormone (PTH) in children. To this end, this study was aimed at evaluating the lowest 25- OHD level that suppresses the production of parathyroid hormone in children. Methods: A retrospective record review was performed for children aged 0.2 to 18 years (n=193; 106 boys and 87 girls) who underwent simultaneous measurements of serum 25-OHD and PTH levels between January 2010 and June 2014. Results: The inflection point of serum 25-OHD level for maximal suppression of PTH was at 18.0 ng/ mL (95% confidence interval, 14.3–21.7 ng/mL). The median PTH level of the children with 25-OHD levels of <18.0 ng/mL was higher than that of children with 25-OHD levels ≥ 18.0 ng/mL (P<0.0001). The median calcium level of children with 25-OHD levels<18.0 ng/mL was lower than that of children with 25-OHD levels≥18.0 ng/mL (P=0.0001). The frequency of hyperparathyroidism was higher in the children with 25-OHD levels<18.0 ng/mL than in the children with 25-OHD levels≥18.0 ng/mL (P<0.0001). Hypocalcemia was more prevalent in the children with 25-OHD levels<18.0 ng/mL than in the children with 25-OHD levels≥18.0 ng/mL (P<0.0001). Conclusion: These data suggest that a vitamin D level of 18.0 ng/mL could be the criterion for 25-OHD deficiency in children at the inflection point of the maximal suppression of PTH. © 2017 by The Korean Pediatric Society. | * |
dc.language | English | * |
dc.publisher | Korean Pediatric Society | * |
dc.subject | Parathyroid hormone | * |
dc.subject | Vitamin D | * |
dc.subject | Vitamin D deficiency | * |
dc.title | The serum level of 25-hydroxyvitamin D for maximal suppression of parathyroid hormone in children: The relationship between 25- hydroxyvitamin D and parathyroid hormone | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 60 | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 45 | * |
dc.relation.lastpage | 49 | * |
dc.relation.journaltitle | Korean Journal of Pediatrics | * |
dc.identifier.doi | 10.3345/kjp.2017.60.2.45 | * |
dc.identifier.scopusid | 2-s2.0-85012971981 | * |
dc.author.google | Kang J.I. | * |
dc.author.google | Lee Y.S. | * |
dc.author.google | Han Y.J. | * |
dc.author.google | Kong K.A. | * |
dc.author.google | Kim H.S. | * |
dc.contributor.scopusid | 김혜순(55663596500) | * |
dc.contributor.scopusid | 공경애(8622974400;57226677267) | * |
dc.date.modifydate | 20240415133154 | * |