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Quality of tri-Co-60 MR-IGRT treatment plans in comparison with VMAT treatment plans for spine SABR

Title
Quality of tri-Co-60 MR-IGRT treatment plans in comparison with VMAT treatment plans for spine SABR
Authors
Choi, Chang HeonPark, So-YeonKim, Jung-InKim, Jin HoKim, KyuboCarlson, JoelPark, Jong Min
Ewha Authors
김규보
SCOPUS Author ID
김규보scopus
Issue Date
2017
Journal Title
BRITISH JOURNAL OF RADIOLOGY
ISSN
0007-1285JCR Link1748-880XJCR Link
Citation
vol. 90, no. 1070
Publisher
BRITISH INST RADIOLOGY
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Objective: To investigate the plan quality of tri-Co-60 intensity-modulated radiation therapy (IMRT) plans for spine stereotactic ablative radiotherapy (SABR). Methods: A total of 20 patients with spine metastasis were retrospectively selected. For each patient, a tri-Co-60 IMRT plan and a volumetric-modulated arc therapy (VMAT) plan were generated. The spinal cords were defined based on MR images for the tri-Co-60 IMRT, while isotropic 1-mm margins were added to the spinal cords for the VMAT plans. The VMAT plans were generated with 10-MV flattening filter-free photon beams of TrueBeam STx (TM) (Varian Medical Systems, Palo Alto, CA), while the tri-Co-60 IMRT plans were generated with the ViewRay (TM) system (ViewRay inc., Cleveland, OH). The initial prescription dose was 18Gy (1 fraction). If the tolerance dose of the spinal cord was not met, the prescription dose was reduced until the spinal cord tolerance dose was satisfied. Results: The mean dose to the target volumes, conformity index and homogeneity index of the VMAT and tri-Co-60 IMRT were 17.8 +/- 0.8 vs 13.7 +/- 3.9 Gy, 0.85 +/- 0.20 vs 1.58 +/- 1.29 and 0.09 +/- 0.04 vs 0.24 +/- 0.19, respectively. The integral doses and beam-on times were 16,570 +/- 1768 vs 22,087 +/- 2.986 Gy cm(3) and 3.95 +/- 1.13 vs 48.82 +/- 10.44 min, respectively. Conclusion: The tri-Co-60 IMRT seems inappropriate for spine SABR compared with VMAT. Advances in knowledge: For spine SABR, the tri-Co-60 IMRT is inappropriate owing to the large penumbra, large leaf width and low dose rate of the ViewRay system.
DOI
10.1259/bjr.20160652
Appears in Collections:
의과대학 > 의학과 > Journal papers
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