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Effectiveness of Capsule Endoscopy Compared with Other Diagnostic Modalities in Patients with Small Bowel Crohn's Disease: A Meta-Analysis

Title
Effectiveness of Capsule Endoscopy Compared with Other Diagnostic Modalities in Patients with Small Bowel Crohn's Disease: A Meta-Analysis
Authors
Choi, MiyoungLim, SungwonChoi, Myung-GyuShim, Ki-NamLee, Seon Heui
Ewha Authors
심기남
SCOPUS Author ID
심기남scopus
Issue Date
2017
Journal Title
GUT AND LIVER
ISSN
1976-2283JCR Link2005-1212JCR Link
Citation
vol. 11, no. 1, pp. 62 - 72
Keywords
Capsule endoscopyDiagnostic yieldMeta-analysisIntestinesmallCrohn disease
Publisher
EDITORIAL OFFICE GUT & LIVER
Indexed
SCIE; SCOPUS; KCI WOS
Abstract
Background/Aims: As a result of the rapid development of medical diagnostic tools, physicians require concrete evidence to evaluate the effectiveness of the tools. We aimed to investigate the effectiveness and additional diagnostic benefits of capsule endoscopy (CE) in patients with small bowel Crohn's disease (CD). Methods: We performed a systematic search of databases, including MEDLINE, EMBASE, and the Cochrane Library, as well as eight domestic databases. Two reviewers independently screened all references. Diagnostic data from the studies were collected, and a meta-analysis was performed. Results: Twenty-four studies were included. In cases of suspected CD, CE demonstrated a superior diagnostic yield compared with small bowel follow-through (SBFT) and enteroclysis (EC); however, there was no difference compared with computed tomography-enterography or magnetic resonance enterography. In cases with established CD, CE demonstrated a higher diagnostic yield only compared with EC. In the detection of terminal ileum lesions, CE exhibited a significantly increased detection rate compared with ileoscopy. Conclusions: The findings of our meta -analysis indicate that CE is superior to SBFT and EC in the evaluation of suspected CD cases. CE is also a more effective diagnostic modality in patients with established CD compared with EC.
DOI
10.5009/gnl16015
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의학전문대학원 > 의학과 > Journal papers
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