Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김규보 | * |
dc.date.accessioned | 2017-02-15T08:02:04Z | - |
dc.date.available | 2017-02-15T08:02:04Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 0167-6806 | * |
dc.identifier.issn | 1573-7217 | * |
dc.identifier.other | OAK-20084 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/234514 | - |
dc.description.abstract | To evaluate the loco-regional recurrence (LRR) rate after breast-conserving surgery without postoperative radiotherapy (RT) for ductal carcinoma in situ (DCIS) of the breast. Between 2000 and 2010, 311 DCIS patients from 9 institutions were analyzed retrospectively. The median age was 47 (range, 20-82). The median tumor size was 7 mm (range, 0.01-76). Margin width was < 1 cm in 85 patients (27.3%), and nuclear grade was high in 37 patients (11.9%). Two hundred and three patients (65.3%) received tamoxifen. With a median follow-up of 74 months (range, 5-189), there were 11 local recurrences (invasive carcinoma in 6 and DCIS in 5) and 1 regional recurrence. The 7-year LRR rate was 3.8%. On univariate analysis, age and margin width were significant risk factors influencing LRR (p = 0.017 and 0.014, respectively). When age and margin width were combined among 211 patients whose margin width were available, the 7-year LRR rates were as follows (p < 0.001): (1) 0% in patients with age > 50 years and any margin width status (n = 64), (2) 1.2% in age <= 50 years and margin width >= 1 cm (n = 93), (3) 13.1% in age <= 50 years and margin width < 1 cm (n = 54). The LRR rate was very low in selected DCIS patients treated with breast-conserving surgery without postoperative RT. However, adjuvant RT should be considered for those with age <= 50 years and margin width < 1 cm. | * |
dc.language | English | * |
dc.publisher | SPRINGER | * |
dc.subject | Ductal carcinoma in situ | * |
dc.subject | Radiation therapy | * |
dc.subject | Age | * |
dc.subject | Resection margin | * |
dc.title | Recurrence outcomes after omission of postoperative radiotherapy following breast-conserving surgery for ductal carcinoma in situ of the breast: a multicenter, retrospective study in Korea (KROG 16-02) | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 162 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 77 | * |
dc.relation.lastpage | 83 | * |
dc.relation.journaltitle | BREAST CANCER RESEARCH AND TREATMENT | * |
dc.identifier.doi | 10.1007/s10549-017-4111-1 | * |
dc.identifier.wosid | WOS:000394137700009 | * |
dc.identifier.scopusid | 2-s2.0-85009257844 | * |
dc.author.google | Kim, Kyubo | * |
dc.author.google | Jung, So-Youn | * |
dc.author.google | Shin, Kyung Hwan | * |
dc.author.google | Kim, Jin Ho | * |
dc.author.google | Han, Wonshik | * |
dc.author.google | Lee, Han-Byoel | * |
dc.author.google | Huh, Seung Jae | * |
dc.author.google | Choi, Doo Ho | * |
dc.author.google | Park, Won | * |
dc.author.google | Ahn, Seung Do | * |
dc.author.google | Kim, Su Ssan | * |
dc.author.google | Kim, Jin Hee | * |
dc.author.google | Suh, Chang-Ok | * |
dc.author.google | Kim, Yong Bae | * |
dc.author.google | Kim, In Ah | * |
dc.author.google | Kim, Suzy | * |
dc.author.google | Kim, Yi-Jun | * |
dc.contributor.scopusid | 김규보(8213302900) | * |
dc.date.modifydate | 20240222162403 | * |