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Sex Difference in the Association Between Brachial Pulse Pressure and Coronary Artery Disease: The Korean Women's Chest Pain Registry (KoROSE)
- Title
- Sex Difference in the Association Between Brachial Pulse Pressure and Coronary Artery Disease: The Korean Women's Chest Pain Registry (KoROSE)
- Authors
- Kim, Hack-Lyoung; Kim, Myung-A; Shim, Wan-Joo; Oh, Sohee; Kim, Mina; Park, Seong Mi; Kim, Yong Hyun; Na, Jin Oh; Shin, Mi Seung; Yoon, Hyun Ju; Shin, Gil Ja; Cho, Yunkyung; Kim, Sung-Eun; Hong, Kyung-Soon; Cho, Kyoung Im
- Ewha Authors
- 신길자
- SCOPUS Author ID
- 신길자
- Issue Date
- 2017
- Journal Title
- JOURNAL OF CLINICAL HYPERTENSION
- ISSN
- 1524-6175
1751-7176
- Citation
- JOURNAL OF CLINICAL HYPERTENSION vol. 19, no. 1, pp. 38 - 44
- Publisher
- WILEY-BLACKWELL
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- This study was performed to investigate the association between brachial pulse pressure (PP) and the presence/extent of obstructive coronary artery disease (CAD) in men and women. Study data were obtained from a nation-wide registry composed of 632 patients (173 men and 459 women, 58.1 +/- 10.5 years) with suspected CAD who underwent invasive coronary angiography. PP was higher in patients with obstructive CAD (>= 50% stenosis) than those without CAD in both sexes (P=.032 in men; P<.001 in women). However, PP increased proportionally with the increasing number of obstructed coronary arteries in women (P<.001) but not in men (P=.070). Multiple logistic-regression analyses demonstrated that higher PP (>= 50.5 mm Hg) was an independent factor for determining obstructive CAD even after controlling for potential confounders in women (odds ratio, 2.83; 95% confidence interval, 1.40-5.73; P=.004). These results were consistent in 173 selected women matched with 173 men based on age and CAD severity. In conclusion, the association between brachial PP and obstructive CAD was more pronounced in women than in men. Brachial PP can be a simple and useful indicator of CAD especially in women. (C) 2016 Wiley Periodicals, Inc.
- DOI
- 10.1111/jch.12862
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
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