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Sex Difference in the Association Between Brachial Pulse Pressure and Coronary Artery Disease: The Korean Women's Chest Pain Registry (KoROSE)

Title
Sex Difference in the Association Between Brachial Pulse Pressure and Coronary Artery Disease: The Korean Women's Chest Pain Registry (KoROSE)
Authors
Kim, Hack-LyoungKim, Myung-AShim, Wan-JooOh, SoheeKim, MinaPark, Seong MiKim, Yong HyunNa, Jin OhShin, Mi SeungYoon, Hyun JuShin, Gil JaCho, YunkyungKim, Sung-EunHong, Kyung-SoonCho, Kyoung Im
Ewha Authors
신길자
SCOPUS Author ID
신길자scopus
Issue Date
2017
Journal Title
JOURNAL OF CLINICAL HYPERTENSION
ISSN
1524-6175JCR Link1751-7176JCR Link
Citation
vol. 19, no. 1, pp. 38 - 44
Publisher
WILEY-BLACKWELL
Indexed
SCIE; SCOPUS WOS scopus
Abstract
This study was performed to investigate the association between brachial pulse pressure (PP) and the presence/extent of obstructive coronary artery disease (CAD) in men and women. Study data were obtained from a nation-wide registry composed of 632 patients (173 men and 459 women, 58.1 +/- 10.5 years) with suspected CAD who underwent invasive coronary angiography. PP was higher in patients with obstructive CAD (>= 50% stenosis) than those without CAD in both sexes (P=.032 in men; P<.001 in women). However, PP increased proportionally with the increasing number of obstructed coronary arteries in women (P<.001) but not in men (P=.070). Multiple logistic-regression analyses demonstrated that higher PP (>= 50.5 mm Hg) was an independent factor for determining obstructive CAD even after controlling for potential confounders in women (odds ratio, 2.83; 95% confidence interval, 1.40-5.73; P=.004). These results were consistent in 173 selected women matched with 173 men based on age and CAD severity. In conclusion, the association between brachial PP and obstructive CAD was more pronounced in women than in men. Brachial PP can be a simple and useful indicator of CAD especially in women. (C) 2016 Wiley Periodicals, Inc.
DOI
10.1111/jch.12862
Appears in Collections:
의과대학 > 의학과 > Journal papers
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