Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 김수정 | - |
dc.date.accessioned | 2017-02-15T08:02:58Z | - |
dc.date.available | 2017-02-15T08:02:58Z | - |
dc.date.issued | 2017 | - |
dc.identifier.issn | 1471-2466 | - |
dc.identifier.other | OAK-20055 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/234486 | - |
dc.description.abstract | Background: Patients with distinctive morphotype were more susceptible to nontuberculous mycobacterial lung disease (NTM-LD). However, little is known about the association between body morphotype and progression of NTM-LD. The aim of this study was to elucidate predictors of NTM-LD progression, focusing on body morphotype and composition. Methods: Data from patients with NTM-LD who participated in NTM cohort which started in 1 July 2011 were analyzed. Patients with more than 6 months of follow up were included for analysis. NTM-LD progression was defined as clinicianinitiated anti-NTM treatment, based on symptomatic and radiologic aggravation. Body morphotype and composition was measured at entry to the cohort using bioelectrical impedance analysis. Results: NTM-LD progressed in 47 out of 150 patients with more than 6 months of follow up. Patients with middle (adjusted hazard ratio [aHR], 2.758; 95% confidence interval [CI], 1.112-6.843) or lowest tertile (aHR, 3.084; 95% CI, 1.241-7. 668) of abdominal fat ratio had a higher risk of disease progression compared with the highest tertile. Other predictors for disease progression were presence of cavity on chest computed tomography (aHR, 4.577; 95% CI, 2.364-8.861), and serum albumin level < 3.5 g/dL (aHR, 12.943; 95% CI, 2.588-64.718). Conclusions: Progression of NTM-LD is associated with body composition. Lower abdominal fat ratio is an independent predictor of NTM-LD progression. | - |
dc.language | English | - |
dc.publisher | BIOMED CENTRAL LTD | - |
dc.subject | Abdominal fat | - |
dc.subject | Anthropometry | - |
dc.subject | Body composition | - |
dc.subject | Nontuberculous mycobacteria | - |
dc.title | Characteristics associated with progression in patients with of nontuberculous mycobacterial lung disease : a prospective cohort study | - |
dc.type | Article | - |
dc.relation.volume | 17 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.journaltitle | BMC PULMONARY MEDICINE | - |
dc.identifier.doi | 10.1186/s12890-016-0349-3 | - |
dc.identifier.wosid | WOS:000391893300004 | - |
dc.identifier.scopusid | 2-s2.0-85008323146 | - |
dc.author.google | Kim, Soo Jung | - |
dc.author.google | Yoon, Soon Ho | - |
dc.author.google | Choi, Sun Mi | - |
dc.author.google | Lee, Jinwoo | - |
dc.author.google | Lee, Chang-Hoon | - |
dc.author.google | Han, Sung Koo | - |
dc.author.google | Yim, Jae-Joon | - |
dc.contributor.scopusid | 김수정(57203772978;57218161842) | - |
dc.date.modifydate | 20220329104030 | - |