Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 이경자 | * |
dc.contributor.author | 김승철 | * |
dc.contributor.author | 문혜성 | * |
dc.contributor.author | 이레나 | * |
dc.contributor.author | 주웅 | * |
dc.contributor.author | 김윤환 | * |
dc.contributor.author | 이지혜 | * |
dc.contributor.author | 박경란 | * |
dc.date.accessioned | 2017-02-15T08:02:57Z | - |
dc.date.available | 2017-02-15T08:02:57Z | - |
dc.date.issued | 2016 | * |
dc.identifier.issn | 2234-1900 | * |
dc.identifier.other | OAK-20048 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/234479 | - |
dc.description.abstract | Purpose: The purpose of this study is to evaluate the treatment outcomes of adjuvant radiotherapy using vaginal brachytherapy (VB) with a lower dose per fraction and/or external beam radiotherapy (EBRT) following surgery for patients with stage I endometrial carcinoma. Materials and Methods: The subjects were 43 patients with the International Federation of Gynecology and Obstetrics (FIGO) stage I endometrial cancer who underwent adjuvant radiotherapy following surgery between March 2000 and April 2014. Of these, 25 received postoperative VB alone, while 18 received postoperative EBRT to the whole pelvis; 3 of these were treated with EBRT plus VB. The median EBRT dose was 50.0 Gy (45.0-50.4 Gy) and the VB dose was 24 Gy in 6 fractions. Tumor dose was prescribed at a depth of 5 mm from the cylinder surface and delivered twice per week. Results: The median follow-up period for all patients was 57 months (range, 9 to 188 months). Five-year disease-free survival (DFS) and overall survival (OS) for all patients were 92.5% and 95.3%, respectively. Adjuvant radiotherapy was performed according to risk factors and stage IB, grade 3 and lymphovascular invasion were observed more frequently in the EBRT group. Five-year DFS for EBRT and VB alone were 88.1% and 96.0%, respectively (p = 0.42), and 5-year OS for EBRT and VB alone were 94.4% and 96%, respectively (p = 0.38). There was no locoregional recurrence in any patient. Two patients who received EBRT and 1 patient who received VB alone developed distant metastatic disease. Two patients who received EBRT had severe complications, one each of grade 3 gastrointestinal complication and pelvic bone insufficiency fracture. Conclusion: Adjuvant radiotherapy achieved high DFS and OS with acceptable toxicity in stage I endometrial cancer. VB (with a lower dose per fraction) may be a viable option for selected patients with early-stage endometrial cancer following surgery. © 2016. The Korean Society for Radiation Oncology. | * |
dc.language | English | * |
dc.publisher | Department of Radiation Oncology | * |
dc.subject | Adjuvant radiotherapy | * |
dc.subject | Conformal radiotherapy | * |
dc.subject | Endometrial cancer | * |
dc.subject | Intracavity radiotherapy | * |
dc.title | Treatment outcomes after adjuvant radiotherapy following surgery for patients with stage i endometrial cancer | * |
dc.type | Article | * |
dc.relation.issue | 4 | * |
dc.relation.volume | 34 | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 265 | * |
dc.relation.lastpage | 272 | * |
dc.relation.journaltitle | Radiation Oncology Journal | * |
dc.identifier.doi | 10.3857/roj.2016.01648 | * |
dc.identifier.scopusid | 2-s2.0-85007578330 | * |
dc.author.google | Kim J. | * |
dc.author.google | Lee K.-J. | * |
dc.author.google | Park K.-R. | * |
dc.author.google | Ha B. | * |
dc.author.google | Kim Y.-J. | * |
dc.author.google | Jung W. | * |
dc.author.google | Lee R. | * |
dc.author.google | Kim S.C. | * |
dc.author.google | Moon H.S. | * |
dc.author.google | Ju W. | * |
dc.author.google | Kim Y.H. | * |
dc.author.google | Lee J. | * |
dc.contributor.scopusid | 이경자(55540780700) | * |
dc.contributor.scopusid | 김승철(35264000100) | * |
dc.contributor.scopusid | 문혜성(14319143700) | * |
dc.contributor.scopusid | 이레나(8694612100) | * |
dc.contributor.scopusid | 주웅(8873659700) | * |
dc.contributor.scopusid | 김윤환(55763947200) | * |
dc.contributor.scopusid | 이지혜(57203145157;56216251300) | * |
dc.contributor.scopusid | 박경란(14040340300;57203047823;57207108839;57308917900) | * |
dc.date.modifydate | 20240419140415 | * |