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Antiadhesive effect of the mixed solution of sodium hyaluronate and sodium carboxymethylcellulose after endoscopic sinus surgery

Title
Antiadhesive effect of the mixed solution of sodium hyaluronate and sodium carboxymethylcellulose after endoscopic sinus surgery
Authors
Kim J.H.Lee J.-H.Yoon J.-H.Chang J.H.Bae J.H.Kim K.-S.
Ewha Authors
배정호
SCOPUS Author ID
배정호scopus
Issue Date
2007
Journal Title
American Journal of Rhinology
ISSN
1050-6586JCR Link
Citation
vol. 21, no. 1, pp. 95 - 99
Indexed
SCOPUS WOS scopus
Abstract
Background: We evaluated the clinical efficacy and safety of the mixed solution of sodium hyaluronate and sodium carboxymethylcellulose (HA-CMC) for prevention of adhesion after endoscopic sinus surgery. Methods: Preoperative computed tomography (CT) scans were graded. At the completion of surgery, HA-CMC was applied to Merocel and repeatedly applied after the removal of Merocel. As a control, normal saline was applied. Endoscopic examination was performed postoperatively and grading was done. Results: The rate of adhesion was the highest at 2 weeks postoperatively and was significantly lower in the HA-CMC-treated group than the control on all postoperative days. The grouping of cases by CT scores at 2 weeks postoperatively showed lower adhesion formation with the HA-CMC treatment than the control. The safety profile of the patients was normal at 4 weeks postoperatively. Conclusion: HA-CMC is an efficacious and safe material in decreasing the incidence of adhesion after endoscopic sinus surgery. Copyright © 2007, OceanSide Publications, Inc., U.S.A.
DOI
10.2500/ajr.2007.21.2911
Appears in Collections:
의과대학 > 의학과 > Journal papers
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