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Topical hydrocortisone and physiotherapy for nonretractile physiologic phimosis in infants

Title
Topical hydrocortisone and physiotherapy for nonretractile physiologic phimosis in infants
Authors
Lee J.W.Cho S.J.Park E.A.Lee S.J.
Ewha Authors
이승주박은애조수진
SCOPUS Author ID
이승주scopusscopus; 박은애scopus; 조수진scopus
Issue Date
2006
Journal Title
Pediatric Nephrology
ISSN
0931-041XJCR Link
Citation
vol. 21, no. 8, pp. 1127 - 1130
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
The effect of hydrocortisone (HC), the steroid of lowest potency, and physiotherapy (PT) on non-retractile physiologic phimosis (PP) and the reduction of subsequent recurrent UTI was evaluated in male infants with UTI. Seventy-eight male infants with febrile UTI and nonretractile PP were prospectively randomized into HC (Plancol, n=39) and control (Vaseline, n=39) groups. Topical application of HC as a thin film around the preputial margin twice a day for four weeks with PT was instructed. The response rate in the HC group was 89.7% (35/39), which was significantly higher than the rate (20.5%; 8/39) in the control group (P<0.05). In the HC group, the response rate was much higher (96.1%) in the subgroup with PT than in the group without PT. Most of the response (88.5%) was observed within two weeks. During the following year, the recurrent rate of UTI was 7.1% (2/28) in the infants with retractile prepuces, which was significantly less than than the rate (29.6%; 8/27) in infants with nonretractile prepuces (P<0.05). In conclusion, topical HC and PT for 2-4 weeks proved to be a simple, safe and effective treatment for nonretractile PP in infants with UTI, and this procedure was beneficial in reducing recurrent UTI. © IPNA 2006.
DOI
10.1007/s00467-006-0104-8
Appears in Collections:
의과대학 > 의학과 > Journal papers
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