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Synthesis of enantiopure pseudo-L-vinylcyclopropyl nucleosides bearing quaternary carbon as potential anti-herpesvirus agent

Title
Synthesis of enantiopure pseudo-L-vinylcyclopropyl nucleosides bearing quaternary carbon as potential anti-herpesvirus agent
Authors
Moon H.R.Park A.-Y.Kim K.R.Chun M.W.Jeong L.S.
Ewha Authors
정낙신
Issue Date
2007
Journal Title
Nucleosides, Nucleotides and Nucleic Acids
ISSN
1525-7770JCR Link
Citation
vol. 26, no. 41495, pp. 975 - 978
Indexed
SCIE; SCOPUS WOS scopus
Abstract
Pseudo-l-vinylcyclopropyl adenine and guanine nucleosides 11 and 12 were designed and enantiopurely synthesized starting from (S)-epichlorohydrin using tandem alkylation, regioselective oxirane-ring opening, and chemoselective reduction as key steps. Copyright © Taylor & Francis Group, LLC.
DOI
10.1080/15257770701508372
Appears in Collections:
약학대학 > 약학과 > Journal papers
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