Synthesis of 2-(3′-Azido- and 3′-Amino-3′-deoxy-β -D-ribofuranosyl)thiazole-4-carboxamide

Abstract

In view of biological activities of tiazofurin and azido or aminosugar nucleosides, novel azido- and amino -substituted tiazofurin derivatives (1 and 2) were efficiently synthesized starting from 1,2; 5,6-di-O-isopropylidene-D-glucose.