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dc.contributor.author김규보*
dc.date.accessioned2016-12-28T02:12:42Z-
dc.date.available2016-12-28T02:12:42Z-
dc.date.issued2016*
dc.identifier.issn0250-7005*
dc.identifier.issn1791-7530*
dc.identifier.otherOAK-19553*
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/233377-
dc.description.abstractAim: To analyze the outcomes of patients with unresectable pancreatic cancer after chemoradiotherapy (CCRT), focusing on sequencing strategy. Patients and Methods: Data of 144 patients treated from January 1989 to December 2013 were retrospectively analyzed. Patients were divided into the scheduled group (N=27), salvage group (N=37) and upfront group (N=80) per CCRT and chemotherapy sequence. Results: With a median follow-up of 10.4 months (range=1.4-164.2), median overall survival (OS) was 13.5 months. Patients in the upfront group had inferior performance status and received a lower radiation dose (p=0.007 and p<0.001, respectively). Higher radiation dose (=45 Gy) was the sole prognosticator related with improved survival in multivariate (p=0.001) analysis, whereas treatment sequence was not a significant prognostic factor (p=0.409). Conclusion: No difference was found among tested sequencing strategies that were all well-tolerated, despite skewed distribution for performance and radiation dose. An upfront approach may be a viable option for patients with limited performance to undergo more active systemic chemotherapy.*
dc.languageEnglish*
dc.publisherINT INST ANTICANCER RESEARCH*
dc.subjectPancreatic cancer*
dc.subjectchemoradiotherapy*
dc.subjectchemotherapy*
dc.subjectradiation dose*
dc.titleOutcome Analysis of Chemoradiation in Unresectable Pancreatic Cancer Focusing on Treatment Sequencing Strategy*
dc.typeArticle*
dc.relation.issue10*
dc.relation.volume36*
dc.relation.indexSCIE*
dc.relation.indexSCOPUS*
dc.relation.startpage5455*
dc.relation.lastpage5461*
dc.relation.journaltitleANTICANCER RESEARCH*
dc.identifier.doi10.21873/anticanres.11125*
dc.identifier.wosidWOS:000388483300059*
dc.identifier.scopusid2-s2.0-84991821820*
dc.author.googleKoh, Hyeon Kang*
dc.author.googleChie, Eui Kyu*
dc.author.googleKim, Kyubo*
dc.author.googleJang, Jin-Young*
dc.author.googleKim, Sun Whe*
dc.author.googleOh, Do-Youn*
dc.author.googleIm, Seock-Ah*
dc.author.googleBang, Yung-Jue*
dc.author.googleHa, Sung W.*
dc.contributor.scopusid김규보(8213302900)*
dc.date.modifydate20240222162403*
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의과대학 > 의학과 > Journal papers
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