Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김규보 | * |
dc.date.accessioned | 2016-12-28T02:12:42Z | - |
dc.date.available | 2016-12-28T02:12:42Z | - |
dc.date.issued | 2016 | * |
dc.identifier.issn | 0250-7005 | * |
dc.identifier.issn | 1791-7530 | * |
dc.identifier.other | OAK-19553 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/233377 | - |
dc.description.abstract | Aim: To analyze the outcomes of patients with unresectable pancreatic cancer after chemoradiotherapy (CCRT), focusing on sequencing strategy. Patients and Methods: Data of 144 patients treated from January 1989 to December 2013 were retrospectively analyzed. Patients were divided into the scheduled group (N=27), salvage group (N=37) and upfront group (N=80) per CCRT and chemotherapy sequence. Results: With a median follow-up of 10.4 months (range=1.4-164.2), median overall survival (OS) was 13.5 months. Patients in the upfront group had inferior performance status and received a lower radiation dose (p=0.007 and p<0.001, respectively). Higher radiation dose (=45 Gy) was the sole prognosticator related with improved survival in multivariate (p=0.001) analysis, whereas treatment sequence was not a significant prognostic factor (p=0.409). Conclusion: No difference was found among tested sequencing strategies that were all well-tolerated, despite skewed distribution for performance and radiation dose. An upfront approach may be a viable option for patients with limited performance to undergo more active systemic chemotherapy. | * |
dc.language | English | * |
dc.publisher | INT INST ANTICANCER RESEARCH | * |
dc.subject | Pancreatic cancer | * |
dc.subject | chemoradiotherapy | * |
dc.subject | chemotherapy | * |
dc.subject | radiation dose | * |
dc.title | Outcome Analysis of Chemoradiation in Unresectable Pancreatic Cancer Focusing on Treatment Sequencing Strategy | * |
dc.type | Article | * |
dc.relation.issue | 10 | * |
dc.relation.volume | 36 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 5455 | * |
dc.relation.lastpage | 5461 | * |
dc.relation.journaltitle | ANTICANCER RESEARCH | * |
dc.identifier.doi | 10.21873/anticanres.11125 | * |
dc.identifier.wosid | WOS:000388483300059 | * |
dc.identifier.scopusid | 2-s2.0-84991821820 | * |
dc.author.google | Koh, Hyeon Kang | * |
dc.author.google | Chie, Eui Kyu | * |
dc.author.google | Kim, Kyubo | * |
dc.author.google | Jang, Jin-Young | * |
dc.author.google | Kim, Sun Whe | * |
dc.author.google | Oh, Do-Youn | * |
dc.author.google | Im, Seock-Ah | * |
dc.author.google | Bang, Yung-Jue | * |
dc.author.google | Ha, Sung W. | * |
dc.contributor.scopusid | 김규보(8213302900) | * |
dc.date.modifydate | 20240222162403 | * |