View : 21 Download: 0

The roles of CD137 signaling in atherosclerosis

Title
The roles of CD137 signaling in atherosclerosis
Authors
Jung I.-H.Oh G.T.
Ewha Authors
오구택
SCOPUS Author ID
오구택scopus
Issue Date
2016
Journal Title
Korean Circulation Journal
ISSN
1738-5520JCR Link
Citation
vol. 46, no. 6, pp. 753 - 761
Keywords
AtherosclerosisCD137Plaque stabilityT cell
Publisher
Korean Society of Circulation
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
The tumor necrosis factor receptor superfamily (TNFRSF), which includes CD40, LIGHT, and OX40, plays important roles in the initiation and progression of cardiovascular diseases, involving atherosclerosis. CD137, a member of TNFRSF, is a well-known activation-induced T cell co-stimulatory molecule and has been reported to be expressed in human atherosclerotic plaque lesions, and plays pivotal roles in mediating disease processes. In this review, we focus on and summarize recent advances in mouse studies on the involvement of CD137 signaling in the pathogenesis and plaque stability of atherosclerosis, thereby highlighting a valuable therapeutic target in atherosclerosis. Copyright © 2016 The Korean Society of Cardiology.
DOI
10.4070/kcj.2016.46.6.753
Appears in Collections:
자연과학대학 > 생명과학전공 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE