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Surgical management of mechanical valve thrombosis: Twenty-six years' experience

Title
Surgical management of mechanical valve thrombosis: Twenty-six years' experience
Authors
Ahn H.Kim K.-H.Kwan C.K.Chang Y.K.
Ewha Authors
김관창
SCOPUS Author ID
김관창scopus
Issue Date
2008
Journal Title
Journal of Korean Medical Science
ISSN
1011-8934JCR Link
Citation
vol. 23, no. 3, pp. 378 - 382
Indexed
SCI; SCIE; SCOPUS; KCI WOS scopus
Abstract
In the present study, the authors investigated the management of mechanical valve thrombosis (MVT). From January 1981 through March 2006, 2,908 mechanical valve replacements were performed in 2,298 patients at our institution. Twenty (0.87%) patients presented with MVT, 14 (70.0%) were women, and the mean age of the patients was 42.0±14.0 (27-66) yr. Thrombosis involved mitral in 14 (70.0%), aortic in 2 (10.0%), tricuspid/aortic in 1 (5%), and tricuspid in 3 (15%). The interval from first operation to valve thrombosis was 121.8±75.4 (0.9-284.7) months. The most frequent clinical presentation was heart failure (13/20, 65%), and predisposing causes of MVT were: poor compliance with warfarin (7), pregnancy (5), drug interaction (2), and unknown (6). All 20 patients underwent valve replacement: mitral (14, 70.0%), tricuspid (3, 15.0%), aortic (2, 10%) and tricuspid/aortic (1, 5%). One early death occurred due to left ventricular failure, but no late mortality occurred during 63.3±49.9 (0.5-165.1) months of follow-up. MVT was treated successfully, and pregnancy and inadequate anticoagulation were found to influence the occurrence of this rare complication. Copyright © The Korean Academy of Medical Sciences.
DOI
10.3346/jkms.2008.23.3.378
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의학전문대학원 > 의학과 > Journal papers
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