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Serum BAFF expression in patients with myasthenia gravis

Title
Serum BAFF expression in patients with myasthenia gravis
Authors
Kim J.Y.Yang Y.Moon J.-S.Lee E.Y.So S.H.Lee H.-S.Park K.D.Choi Y.-C.
Ewha Authors
박기덕이홍수
SCOPUS Author ID
박기덕scopus; 이홍수scopus
Issue Date
2008
Journal Title
Journal of Neuroimmunology
ISSN
0165-5728JCR Link
Citation
vol. 199, no. 41276, pp. 151 - 154
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
A B-cell activating factor of the tumor necrosis factor (TNF) family (BAFF) is an essential B-cell survival factor. Myasthenia gravis (MG) is one of the most typical antibody-mediated autoimmune disorders. To test whether serum BAFF levels are increased in MG patients, we compared the serum BAFF levels of 40 MG patients with those of 30 healthy controls. Serum BAFF levels of MG group were significantly higher than those of healthy group. These results suggested that the BAFF might play a role in the immunopathogenesis of MG and further study on B-cell and T-cell activation may be needed. © 2008 Elsevier B.V. All rights reserved.
DOI
10.1016/j.jneuroim.2008.05.010
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
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