View : 13 Download: 0

Lowering prostate-specific antigen threshold for prostate biopsy in Korean men: Impact on the number needing biopsy

Title
Lowering prostate-specific antigen threshold for prostate biopsy in Korean men: Impact on the number needing biopsy
Authors
Cho J.S.Kim S.I.Kim S.J.Kim Y.S.Kim C.I.Kim H.S.Seong D.H.Song Y.S.Lee D.H.Yang W.J.Cheon S.H.Cho K.S.Cho I.R.Chung B.H.Choi Y.D.Im H.Hong S.J.
Ewha Authors
이동현
SCOPUS Author ID
이동현scopus
Issue Date
2008
Journal Title
Korean Journal of Urology
ISSN
0494-4747JCR Link
Citation
vol. 49, no. 2, pp. 118 - 121
Indexed
SCOPUS scopus
Abstract
Purpose: We examined the effect of lowering prostate-specific antigen (PSA) threshold on the number of Korean men requiring a prostate biopsy. Materials and methods: We evaluated men who had serum PSA levels tested at routine physical check-ups between 1999 and 2005 at 11 domestic hospitals. Men with PSA ≥ 10ng/ml or patients with prostate cancer were excluded. A total of 45,074 men (aged 50 to 79 years) were enrolled and split into three age groups: 50-59 years, 60-69 years, and 70-79 years. For each age group, we calculated the number and proportion of men whose PSA level exceeded potential biopsy thresholds: 2.5ng/ml, 3.0ng/ml, and 4.0ng/ml. Results were extrapolated to the 4.992 million men older than 50 years old, or 21.3% of the Korean male population in 2005. Results: The number of biopsy candidates at the threshold of 4.0ng/ ml, 3.0ng/ml, and 2.5ng/ml were 1,321 (2.9%), 2,248 (5.4%), and 3,577 (7.9%), respectively. Extrapolating to the male population in Korea, lowering the PSA threshold from 4.0ng/ml to 3.0 or 2.5ng/ml would increase the number of men needing biopsy by 1.75 and 2.49 times, respectively. Conclusions: Lowering the PSA threshold would increase the number of men receiving prostate biopsy despite the low reference age for PSA in Korea. Considering the low incidence of prostate cancer, physicians should be careful in altering the PSA threshold.
Appears in Collections:
의학전문대학원 > 의학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE