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A case of persistent hiccup in a patient with non-small cell lung cancer

Title
A case of persistent hiccup in a patient with non-small cell lung cancer
Authors
Hye S.P.Yun S.S.So Y.L.Jung Y.J.Sung S.K.Sun H.R.Yoo R.K.Eun M.C.Jin H.L.Yon J.R.Dong E.S.Jin W.M.
Ewha Authors
이진화천은미류연주송동은
SCOPUS Author ID
이진화scopus; 천은미scopus; 류연주scopus
Issue Date
2008
Journal Title
Tuberculosis and Respiratory Diseases
ISSN
1738-3536JCR Link
Citation
vol. 64, no. 1, pp. 39 - 43
Indexed
SCOPUS; KCI scopus
Abstract
A hiccup is caused by involuntary, intermittent, and spasmodic contractions of the diaphragm and intercostal muscles. It starts with a sudden inspiration and ends with an abrupt closure of the glottis. Even though a hiccup is thought to develop through the hiccup reflex arc, its exact pathophysiology is still unclear. The etiologies include gastrointestinal disorders, respiratory abnormalities, psychogenic factors, toxic-metabolic disorders, central nervous system dysfunctions and irritation of the vagus and phrenic nerves. Most benign hiccups can be controlled by traditional empirical therapy such as breath holding and swallowing water. However, though rare, a persistent hiccup longer than 48 hours can lead to significant adverse effects including malnutrition, dehydration, insomnia, electrolyte imbalance, and cardiac arrhythmia. An intractable hiccup can sometimes even cause death. We herein describe a patient with non-small cell lung cancer who was severely distressed by a persistent hiccup.
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의과대학 > 의학과 > Journal papers
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