Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김범산 | * |
dc.contributor.author | 윤혜전 | * |
dc.date.accessioned | 2016-11-18T02:11:52Z | - |
dc.date.available | 2016-11-18T02:11:52Z | - |
dc.date.issued | 2017 | * |
dc.identifier.issn | 0914-7187 | * |
dc.identifier.issn | 1864-6433 | * |
dc.identifier.other | OAK-19431 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/232783 | - |
dc.description.abstract | This study aimed to evaluate the prognostic value of F-18 FDG PET/CT in comparison with Tc-99m sestamibi breast-specific gamma imaging (BSGI) and previously established clinical prognostic parameters of invasive ductal breast carcinoma (IDC). We retrospectively included 157 female IDC patients (mean age 49.2 years, range 29.9-78.9) who underwent PET/CT and BSGI. The maximum standardized uptake value (SUVmax) and tumor to normal background ratios (TNRs) of their primary tumors were measured on PET/CT and BSGI, respectively. Univariate and multivariate survival analyses were performed to evaluate the prognostic value of the measured parameters and other clinical prognostic factors: age, menopausal status, breast density, pathologic tumor size (pTS), axillary nodal status (ANS), nuclear grade, histologic grade, hormone receptor status of estrogen (ER) and progesterone receptors (PR) and HER-2 expression. Among 157 patients, recurrences occurred in 22 patients (14.0 %). In univariate analyses, pTS (p < 0.0001), ANS (p < 0.0001), nuclear grade (p = 0.0046), histologic grade (p = 0.0001), ER status (p < 0.0001), PR status (p = 0.0037), HER-2 status (p = 0.0007), primary tumor SUVmax (p < 0.0001) and TNR (p = 0.0001) were significant predictors of recurrence. Among them, pTS (p = 0.0172), ANS (p = 0.0416), ER status (p = 0.0375) and primary tumor SUVmax (p = 0.0239) were independent prognostic factors in multivariate regression analysis. High primary tumor SUVmax of PET/CT and high TNR of BSGI were poor prognostic factors in IDC patients; in addition, primary tumor SUVmax was an independent prognostic factor along with pTS, ANS and ER status. | * |
dc.language | English | * |
dc.publisher | SPRINGER | * |
dc.subject | F-18 FDG PET/CT | * |
dc.subject | Tc-99m sestamibi breast-specific gamma imaging | * |
dc.subject | Invasive ductal breast carcinoma | * |
dc.subject | Prognostic factor | * |
dc.subject | Recurrence-free survival | * |
dc.title | Prognostic value of primary tumor SUVmax on F-18 FDG PET/CT compared with semi-quantitative tumor uptake on Tc-99m sestamibi breast-specific gamma imaging in invasive ductal breast cancer | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 31 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 19 | * |
dc.relation.lastpage | 28 | * |
dc.relation.journaltitle | ANNALS OF NUCLEAR MEDICINE | * |
dc.identifier.doi | 10.1007/s12149-016-1127-2 | * |
dc.identifier.wosid | WOS:000392289900003 | * |
dc.identifier.scopusid | 2-s2.0-84988329609 | * |
dc.author.google | Yoo, Jang | * |
dc.author.google | Yoon, Hai-Jeon | * |
dc.author.google | Kim, Bom Sahn | * |
dc.contributor.scopusid | 김범산(35223582600) | * |
dc.contributor.scopusid | 윤혜전(47161772300) | * |
dc.date.modifydate | 20240222164135 | * |