Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 하은희 | * |
dc.date.accessioned | 2016-10-20T02:10:39Z | - |
dc.date.available | 2016-10-20T02:10:39Z | - |
dc.date.issued | 2009 | * |
dc.identifier.issn | 1055-9965 | * |
dc.identifier.other | OAK-5417 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/232546 | - |
dc.description.abstract | High-density lipoprotein cholesterol (HDL-C) has been suggested to be associated with breast cancer. However, the roles of HDL-C and hypertriglyceridemia on breast cancer still have been controversial. The goal of this study was to investigate the association between HDL-C with breast cancer risk, stratifying by menopausal status, and body mass index. The hormonal receptor status of breast has been proposed to modify the effect of HDL-C on breast cancer. Multicenter hospital-based case-control study was conducted from November 2004 to December 2005 in Korea. After one to two individual matchings by age (±5 years) and menopausal status, 690 cases and 1,380 controls were included in the analysis. Odds ratios (OR) and 95% confidence intervals (95% CI) were estimated by conditional, unconditional, and multinomial logistic regressions. Protective effect of HDL-C on breast cancer was only observed among premenopausal women with an OR (95% CI) of 0.49 (0.33-0.72) for HDL-C ≥60 versus <50 mg/dL (Ptrend < 0.01). Only nonobese premenopausal women had a significant decreased risk (OR, 0.34; 95% CI, 0.22-0.53). OR (95% CI) of low HDL-C (<50 mg/dL) and high triglyceride (TG; ≥150 mg/dL) category was 2.20 (1.32-3.67) on estrogen receptor-negative and progesterone receptor-negative breast cancer compared with high HDL-C (≥50 mg/dL) and low TG (<150 mg/dL) category. This study suggests that higher level of HDL-C may reduce breast cancer risk among premenopausal women. Estrogen receptor-negative and progesterone receptor-negative breast cancer was associated with dyslipidemia, which implicates that association among HDL-C, TG, and breast cancer may be modified by eceptor status. Copyright © 2009 American Association for Cancer Research. | * |
dc.language | English | * |
dc.title | Serum high-density lipoprotein cholesterol and breast cancer risk by menopausal status, body mass index, and hormonal receptor in Korea | * |
dc.type | Article | * |
dc.relation.issue | 2 | * |
dc.relation.volume | 18 | * |
dc.relation.index | SCI | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 508 | * |
dc.relation.lastpage | 515 | * |
dc.relation.journaltitle | Cancer Epidemiology Biomarkers and Prevention | * |
dc.identifier.doi | 10.1158/1055-9965.EPI-08-0133 | * |
dc.identifier.wosid | WOS:000263547800018 | * |
dc.identifier.scopusid | 2-s2.0-60549099737 | * |
dc.author.google | Kim Y. | * |
dc.author.google | Park S.K. | * |
dc.author.google | Han W. | * |
dc.author.google | Kim D.-H. | * |
dc.author.google | Hong Y.-C. | * |
dc.author.google | Ha E.H. | * |
dc.author.google | Ahn S.-H. | * |
dc.author.google | Noh D.-Y. | * |
dc.author.google | Kang D. | * |
dc.author.google | Yoo K.-Y. | * |
dc.contributor.scopusid | 하은희(7003615774) | * |
dc.date.modifydate | 20240415125553 | * |