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Lidocaine given intravenously improves conditions for laryngeal mask airway insertion during propofol target-controlled infusion

Title
Lidocaine given intravenously improves conditions for laryngeal mask airway insertion during propofol target-controlled infusion
Authors
Baik H.J.Kim Y.J.Kim J.H.
Ewha Authors
김종학백희정김윤진
SCOPUS Author ID
김종학scopus; 백희정scopus; 김윤진scopus
Issue Date
2009
Journal Title
European Journal of Anaesthesiology
ISSN
0265-0215JCR Link
Citation
vol. 26, no. 5, pp. 377 - 381
Indexed
SCIE; SCOPUS WOS scopus
Abstract
Background and objective Patient response to laryngeal mask airway insertion during propofol induction depends on many factors. Lidocaine has been used to reduce cardiovascular responses, coughing, and bucking induced by tracheal intubation. The aim of this study was to determine the effects of intravenous lidocaine on laryngeal mask airway insertion conditions during the induction of anaesthesia with propofol target-controlled infusion. Methods Eighty patients, 16-54 years of age, weighing between 45 and 100 kg, who underwent minor surgery, were randomly divided into two groups (the lidocaine and control groups). Anaesthesia was induced with propofol target- controlled infusion at a target plasma concentration of 6 μ-gml-1. The lidocaine group received 1.5mgkg-1 of lidocaine 50 s after starting target-controlled infusion and the control group received an equivalent volume of saline. Laryngeal mask airways were inserted when propofol effect-site concentrations reached 2.5 μ-gml-1. Laryngeal mask airway insertion conditions (mouth opening, gagging, coughing, movements, laryngospasm, overall ease of insertion, and hiccups) were assessed, and haemodynamic responses were monitored for 3 min after laryngeal mask airway insertion. Results No significant differences were observed between the two groups in terms of hemodynamic responses. However, the lidocaine group showed lower incidences of coughing (5 vs. 22.5%), gagging (25 vs. 55%), and laryngospasm (2.5 vs. 17.5%) (P<0.05). Conclusion Pretreatment with intravenous lidocaine 1.5 mg kg-1 during induction with propofol target-controlled infusion improves laryngeal mask airway insertion conditions. Eur J Anaesthesiol 26:377-381 © 2009 European Society of Anaesthesiology.
DOI
10.1097/EJA.0b013e32831dcd4d
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의학전문대학원 > 의학과 > Journal papers
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