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Building the SeqChromMM Markov property atlas of the human genome by analyzing the 200-bp units of the 15 different chromatin regions of ENCODE

Title
Building the SeqChromMM Markov property atlas of the human genome by analyzing the 200-bp units of the 15 different chromatin regions of ENCODE
Authors
Lee, K. -E.Park, H. -S.
Ewha Authors
박현석
SCOPUS Author ID
박현석scopus
Issue Date
2016
Journal Title
GENETICS AND MOLECULAR RESEARCH
ISSN
1676-5680JCR Link
Citation
vol. 15, no. 3
Keywords
Chromatin mapsNucleotide frequency patternsMarkov chainNoncoding DNAComputational epigenetics
Publisher
FUNPEC-EDITORA
Indexed
SCIE; SCOPUS WOS scopus
Abstract
We analyzed the publicly available ChromHMM BED files of the ENCODE project and tested the Markov properties of the different chromatin states in the human genome. Nucleotide frequency profiles of regional chromatin segmentations were analyzed, and Markov chains were built to detect Markov properties in the chromatin states of different ChromHMM regions. By estimating the transition probabilities of 200-base pair nucleotide sequences of the human genome, we constructed a nucleotide-sequence-based Markovian chromatin map called SeqChromMM.
DOI
10.4238/gmr.15038992
Appears in Collections:
엘텍공과대학 > 컴퓨터공학과 > Journal papers
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