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Superior outcomes of kidney transplantation compared with dialysis An optimal matched analysis of a national population-based cohort study between 2005 and 2008 in Korea

Title
Superior outcomes of kidney transplantation compared with dialysis An optimal matched analysis of a national population-based cohort study between 2005 and 2008 in Korea
Authors
Yoo, Kyung DonKim, Clara TammyKim, Myoung-HeeNoh, JunhyugKim, GunheeKim, HoAn, Jung NamPark, Jae YoonCho, HyunjeongKim, Kyoung HoonKim, HyunwookRyu, Dong-RyeolKim, Dong KiLim, Chun SooKim, Yon SuLee, Jung Pyo
Ewha Authors
류동열
SCOPUS Author ID
류동열scopus
Issue Date
2016
Journal Title
MEDICINE
ISSN
0025-7974JCR Link1536-5964JCR Link
Citation
vol. 95, no. 33
Keywords
dialysiskidney transplantationmortality
Publisher
LIPPINCOTT WILLIAMS & WILKINS
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Data regarding kidney transplantation (KT) and dialysis outcomes are rare in Asian populations. In the present study, we evaluated the clinical outcomes associated with KT using claims data from the Korean national public health insurance program. Among the 35,418 adult patients with incident dialysis treated between 2005 and 2008 in Korea, 1539 underwent KT. An optimal balanced risk set matching was attempted to compare the transplant group with the control group in terms of the overall survival and major adverse cardiac event-free survival. Before matching, the dialysis group was older and had more comorbidities. After matching, there were no differences in age, sex, dialysis modalities, or comorbidities. Patient survival was significantly better in the transplant group than in the matched control group (P<0.001). In addition, the transplant group showed better major adverse cardiac event-free survival than the dialysis group (P<0.001; hazard ratio, 0.49; 95% confidence interval, 0.32-0.75). Korean patients with incident dialysis who underwent long-term dialysis had significantly more cardiovascular events and higher all-cause mortality rates than those who underwent KT. Thus, KT should be more actively recommended in Korean populations.
DOI
10.1097/MD.0000000000004352
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의학전문대학원 > 의학과 > Journal papers
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