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111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women

Title
111/121 diplotype of Calpain-10 is associated with the risk of polycystic ovary syndrome in Korean women
Authors
Lee J.Y.Lee W.J.Hur S.E.Lee C.M.Sung Y.-A.Chung H.W.
Ewha Authors
성연아정혜원
SCOPUS Author ID
성연아scopus; 정혜원scopus
Issue Date
2009
Journal Title
Fertility and Sterility
ISSN
0015-0282JCR Link
Citation
vol. 92, no. 2, pp. 830 - 833
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
We investigated whether the CAPN-10 polymorphism UCSNP-43, -19, and -63 contribute, either individually or as haplotype/diplotype, to the susceptibility of polycystic ovary syndrome (PCOS) or related quantitative traits in Korean women. Our data showed that 111 haplotype and 111/121 and 111/111 diplotypes in the CAPN-10 gene were associated with a significantly increased risk of PCOS, and 112 haplotype and 121/121 and 112/122 diplotypes were associated with decreased risk of PCOS in the Korean population. © 2009 American Society for Reproductive Medicine.
DOI
10.1016/j.fertnstert.2008.06.023
Appears in Collections:
의과대학 > 의학과 > Journal papers
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