Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 정병문 | * |
dc.date.accessioned | 2016-08-29T11:08:56Z | - |
dc.date.available | 2016-08-29T11:08:56Z | - |
dc.date.issued | 2009 | * |
dc.identifier.issn | 0959-9428 | * |
dc.identifier.other | OAK-5830 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/232032 | - |
dc.description.abstract | A reverse thermogelling polymer aqueous solution is a free-flowing sol at a low temperature and becomes a semisolid gel as the temperature increases. It is expected to be a very promising biomaterial as a minimally invasive injectable system for drug delivery and tissue engineering applications. The principles of materials design are (1) balancing the hydrophobicity and hydrophilicty of a polymer, (2) controlling the topology of a polymer, (3) matching the degradation kinetics of a polymer with a specific biomedical application, and (4) controlling the biocompatibility of the material with a drug as well as a host. This article covers recent progress of reverse theromogelling biodegradable polymers based on aliphatic polyesters, polyphosphazenes, poloxamer derivatives, polysaccharides, polypeptides, poly(propylene phosphate)s, polyorthoesters, polycarbonates, polycyanoacrylates, and poly(N-(2-hydroxyethyl) methacrylamide-lactate)s. The material characteristics, driving forces or mechanism for sol-gel transition, and their biomedical applications are summarized. In addition, the authors' perspectives on future reverse theromogelling materials design are suggested. © The Royal Society of Chemistry 2009. | * |
dc.language | English | * |
dc.title | Reverse thermogelling biodegradable polymer aqueous solutions | * |
dc.type | Article | * |
dc.relation.issue | 33 | * |
dc.relation.volume | 19 | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 5891 | * |
dc.relation.lastpage | 5905 | * |
dc.relation.journaltitle | Journal of Materials Chemistry | * |
dc.identifier.doi | 10.1039/b902208b | * |
dc.identifier.wosid | WOS:000268885900003 | * |
dc.identifier.scopusid | 2-s2.0-68749094066 | * |
dc.author.google | Joo M.K. | * |
dc.author.google | Park M.H. | * |
dc.author.google | Choi B.G. | * |
dc.author.google | Jeong B. | * |
dc.contributor.scopusid | 정병문(7102237959) | * |
dc.date.modifydate | 20240118155902 | * |