Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 서주영 | * |
dc.contributor.author | 유경하 | * |
dc.contributor.author | 우소연 | * |
dc.contributor.author | 조수진 | * |
dc.date.accessioned | 2016-08-29T11:08:47Z | - |
dc.date.available | 2016-08-29T11:08:47Z | - |
dc.date.issued | 2009 | * |
dc.identifier.issn | 1065-6995 | * |
dc.identifier.other | OAK-5279 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/231854 | - |
dc.description.abstract | Restricted numbers and poor regenerative properties limit the use of adult stem cells. We tested the effect of hypoxic treatment as a method by which to increase cell migration. Bone marrow cells (BMCs) were cultured under oxygen saturations of 0.1, 3, and 20% for 24 h. After hypoxic treatment, BMCs of apoptotic fraction were decreased. The expression of CXCR4 was noticeably increased in the hypoxia-treated BMCs and their migration in response to SDF-1α was enhanced compared with cells cultured under normoxic condition. Hypoxic BMCs had a higher degree of engraftment to the CCl 4-injured liver than the normoxic cells. Hypoxic treatment of BMCs may have merits in decreasing apoptosis of those cells as well as in enhancing cellular migration to SDF-1α, the chemokine which binds to BMCs expressed CXCR4 and to the injured tissue, such as CCl 4 damaged liver. © 2008 International Federation for Cell Biology. | * |
dc.language | English | * |
dc.title | Effect of hypoxic treatment on bone marrow cells that are able to migrate to the injured liver | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 33 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 31 | * |
dc.relation.lastpage | 35 | * |
dc.relation.journaltitle | Cell Biology International | * |
dc.identifier.doi | 10.1016/j.cellbi.2008.10.002 | * |
dc.identifier.wosid | WOS:000261949000004 | * |
dc.identifier.scopusid | 2-s2.0-57649155507 | * |
dc.author.google | Ju S.-Y. | * |
dc.author.google | Cho K.-A. | * |
dc.author.google | Cho S.J. | * |
dc.author.google | Jung Y.-J. | * |
dc.author.google | Woo S.-Y. | * |
dc.author.google | Seoh J.-Y. | * |
dc.author.google | Han H.-S. | * |
dc.author.google | Ryu K.-H. | * |
dc.contributor.scopusid | 서주영(6603709174;57209001625) | * |
dc.contributor.scopusid | 유경하(14038236200) | * |
dc.contributor.scopusid | 우소연(7402853365) | * |
dc.contributor.scopusid | 조수진(35200321000) | * |
dc.date.modifydate | 20240118130224 | * |