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dc.contributor.author서주영-
dc.contributor.author유경하-
dc.contributor.author우소연-
dc.contributor.author조수진-
dc.date.accessioned2017-08-28T19:36:51Z-
dc.date.available2017-08-28T19:36:51Z-
dc.date.issued2009-
dc.identifier.issn1065-6995-
dc.identifier.otherOAK-5279-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/231854-
dc.description.abstractRestricted numbers and poor regenerative properties limit the use of adult stem cells. We tested the effect of hypoxic treatment as a method by which to increase cell migration. Bone marrow cells (BMCs) were cultured under oxygen saturations of 0.1, 3, and 20% for 24 h. After hypoxic treatment, BMCs of apoptotic fraction were decreased. The expression of CXCR4 was noticeably increased in the hypoxia-treated BMCs and their migration in response to SDF-1α was enhanced compared with cells cultured under normoxic condition. Hypoxic BMCs had a higher degree of engraftment to the CCl 4-injured liver than the normoxic cells. Hypoxic treatment of BMCs may have merits in decreasing apoptosis of those cells as well as in enhancing cellular migration to SDF-1α, the chemokine which binds to BMCs expressed CXCR4 and to the injured tissue, such as CCl 4 damaged liver. © 2008 International Federation for Cell Biology.-
dc.languageEnglish-
dc.titleEffect of hypoxic treatment on bone marrow cells that are able to migrate to the injured liver-
dc.typeArticle-
dc.relation.issue1-
dc.relation.volume33-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage31-
dc.relation.lastpage35-
dc.relation.journaltitleCell Biology International-
dc.identifier.doi10.1016/j.cellbi.2008.10.002-
dc.identifier.wosidWOS:000261949000004-
dc.identifier.scopusid2-s2.0-57649155507-
dc.author.googleJu S.-Y.-
dc.author.googleCho K.-A.-
dc.author.googleCho S.J.-
dc.author.googleJung Y.-J.-
dc.author.googleWoo S.-Y.-
dc.author.googleSeoh J.-Y.-
dc.author.googleHan H.-S.-
dc.author.googleRyu K.-H.-
dc.contributor.scopusid서주영(6603709174)-
dc.contributor.scopusid유경하(14038236200)-
dc.contributor.scopusid우소연(7402853365)-
dc.contributor.scopusid조수진(35200321000)-
dc.date.modifydate20181002081005-
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의과대학 > 의학과 > Journal papers
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