View : 48 Download: 0

Minireview: Syndecans and their crucial roles during tissue regeneration

Title
Minireview: Syndecans and their crucial roles during tissue regeneration
Authors
Chung, HeesungMulthaupt, Hinke A. B.Oh, Eok-SooCouchman, John R.
Ewha Authors
오억수정희성
SCOPUS Author ID
오억수scopus
Issue Date
2016
Journal Title
FEBS LETTERS
ISSN
0014-5793JCR Link1873-3468JCR Link
Citation
vol. 590, no. 15, pp. 2408 - 2417
Keywords
extracellular matrixgrowth factorsyndecan
Publisher
WILEY-BLACKWELL
Indexed
SCI; SCIE; SCOPUS WOS scopus
Abstract
Syndecans are transmembrane heparan sulfate proteoglycans, with roles in development, tumorigenesis and inflammation, and growing evidence for involvement in tissue regeneration. This is a fast developing field with the prospect of utilizing tissue engineering and biomaterials in novel therapies. Syndecan receptors are not only ubiquitous in mammalian tissues, regulating cell adhesion, migration, proliferation, and differentiation through independent signaling but also working alongside other receptors. Their importance is highlighted by an ability to interact with a diverse array of ligands, including extracellular matrix glycoproteins, growth factors, morphogens, and cytokines that are important regulators of regeneration. We also discuss the potential for syndecans to regulate stem cell properties, and suggest that understanding these proteoglycans is relevant to exploiting cell, tissue, and materials technologies.
DOI
10.1002/1873-3468.12280
Appears in Collections:
자연과학대학 > 생명과학전공 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE