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Clinical Effect of Add-On Primovist-Enhanced Magnetic Resonance Imaging on Preoperative Tumor Staging in Hepatocellular Carcinoma Patients
- Clinical Effect of Add-On Primovist-Enhanced Magnetic Resonance Imaging on Preoperative Tumor Staging in Hepatocellular Carcinoma Patients
- Jin, Young-Joo; Lee, Jin-Woo; Kwon, Oh Sang; Jung, Young Kul; Kwon, Jung Hyun; Jang, Jeong Won; Kim, Young Seok; Kim, Tae Hun; Jeon, Yong Sun
- Ewha Authors
- SCOPUS Author ID
- Issue Date
- Journal Title
- JOURNAL OF SURGICAL ONCOLOGY
- 0022-4790; 1096-9098
- vol. 114, no. 1, pp. 106 - 111
- hepatocellular carcinoma; primovist-enhanced magnetic resonance imaging; Barcelona clinic liver cancer; liver dynamic computed tomography
- SCI; SCIE; SCOPUS
- Background/Aims: We analyzed the incidence of change of Barcelona Clinic Liver Cancer (BCLC) stage after add-on Primovist-enhanced magnetic resonance imaging (MRI) in hepatocellular carcinoma (HCC) patients with Barcelona Clinic Liver Cancer stage 0 or A as determined by liver dynamic computed tomography (LDCT). Methods: Atotal of 166 patients enrolled prospectively between August 2012 and December 2014 were retrospectively analyzed. The rates of stage change after Primovist-enhanced MRI and the treatment finally adopted in patients with stage change were evaluated. Results: Of the 166 patients, 24 (18.6%) had truly new HCCs. Forty-six (27.7%) and 120 (72.3%) patients had BCLC stages 0 and A, respectively, before Primovist-enhanced MRI, but after Primovist-enhanced MRI, 28 (16.9%), 134 (80.7%), and 4 (2.4%) patients had BCLC stages 0, A, and B, respectively. Tumor stage changed in 22 (13.3%) patients, from 0 to A (18, 39.1%) or A to B (4, 3.3%). Conclusions: Add-on Primovist-enhanced magnetic resonance imaging can change BCLC stage with 13.3% in patients with BCLC 0 or A staged HCC, as determined by LDCT. (C) 2016 Wiley Periodicals, Inc.
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