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Higher blood pressure variability in white coat hypertension; from the Korean Ambulatory Blood Pressure Monitoring Registry

Title
Higher blood pressure variability in white coat hypertension; from the Korean Ambulatory Blood Pressure Monitoring Registry
Authors
Kang I.S.Pyun W.B.Shin J.Ihm S.-H.Kim J.H.Park S.Kim K.-I.Kim W.-S.Kim S.G.Shin G.J.
Ewha Authors
신길자편욱범
SCOPUS Author ID
신길자scopus; 편욱범scopus
Issue Date
2016
Journal Title
Korean Circulation Journal
ISSN
1738-5520JCR Link
Citation
vol. 46, no. 3, pp. 365 - 373
Keywords
AmbulatoryBlood pressure monitoringBlood pressure variabilityWhite coat hypertension
Publisher
Korean Society of Circulation
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
Background and Objectives: Blood pressure variability (BPV) was recently shown to be a risk factor of stroke. White coat hypertension (WCH) used to be regarded as innocuous, but one long-term follow-up study reported that WCH increased stroke rate compared to normotension (NT). In this study, we aimed to evaluate the relationship between WCH and BPV. Subjects and Methods: We analyzed 1398 subjects from the Korean Ambulatory Blood Pressure Registry, who were divided into NT (n=364), masked hypertension (n=122), white coat hypertension (n=254), and sustained hypertension (n=658) groups. Results: Baseline characteristics were similar among groups. The average real variability (ARV), a highly sensitive BPV parameter, was highest in the WCH group, followed by the sustained hypertension, masked hypertension, and NT groups. The results persisted after being adjusted for covariates. The WCH vs. sustained hypertension results (adjusted mean±standard error) were as follows: 24-h systolic ARV, 22.9±0.8 vs. 19.4±0.6; 24-h diastolic ARV, 16.8±0.6 vs. 14.3±0.5; daytime systolic ARV, 21.8±0.8 vs. 16.8±0.6; and daytime diastolic ARV, 16.2±0.6 vs. 13.4±0.5 (p<0.001 for all comparisons). Conclusion: From the registry data, we found that subjects with WCH or masked hypertension had higher BPV than NT. However, long-term follow-up data assessing the clinical influences of WCH on stroke are needed. Copyright © 2016 The Korean Society of Cardiology.
DOI
10.4070/kcj.2016.46.3.365
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의학전문대학원 > 의학과 > Journal papers
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