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dc.contributor.author하은희-
dc.date.accessioned2017-08-28T08:07:37Z-
dc.date.available2017-08-28T08:07:37Z-
dc.date.issued2016-
dc.identifier.issn1368-9800-
dc.identifier.issn1475-2727-
dc.identifier.otherOAK-18553-
dc.identifier.urihttp://dspace.ewha.ac.kr/handle/2015.oak/231536-
dc.description.abstractObjective: Polycyclic aromatic hydrocarbons (PAH) are common dietary exposures that cross the human placenta and are classified as a probable human carcinogen. The aim of the present study was to investigate the potential impact of exposure to PAH-containing meat consumed during pregnancy on birth outcomes. Design: Prospective birth cohort study. Only non-smoking women with singleton pregnancies, who were free from chronic disease such as diabetes and hypertension, were included in the study. Maternal consumption of PAH-rich meat was estimated through FFQ. Multiple linear regression was used to assess factors related to higher intake and the association between dietary PAH and birth outcomes. Setting: Republic of Korea, 2006-2011. Subjects: Pregnant women (n 778) at 12-28 weeks of gestation enrolled in the Mothers and Children's Environmental Health (MOCEH) study. Results: The multivariable regression model showed a significant reduction in birth weight associated with higher consumption level of foods rich in PAH, such as grilled or roasted meat, during pregnancy (beta-17.48 g, P < 0.05 for every 1 point higher in meat score). Further adjusting for biomarkers of airborne PAH did not alter this association. There was no evidence that higher consumption level of PAH-rich meat shortens the duration of gestation (P = 0.561). Regression models performed for birth length and head circumference produced negative effects that were not statistically significant. Conclusions: Consumption of higher levels of barbecued, fried, roasted and smoked meats during pregnancy was associated with reduced birth weight. Dietary risk of PAH exposure in Korean women is of concern.-
dc.languageEnglish-
dc.publisherCAMBRIDGE UNIV PRESS-
dc.subjectBiomarker-
dc.subjectChildren-
dc.subjectPolycyclic aromatic hydrocarbons-
dc.subjectPAH-rich meat-
dc.subjectPregnancy-
dc.subjectBirth weight-
dc.titleImpact of prenatal exposure to polycyclic aromatic hydrocarbons from maternal diet on birth outcomes: a birth cohort study in Korea-
dc.typeArticle-
dc.relation.issue14-
dc.relation.volume19-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage2562-
dc.relation.lastpage2571-
dc.relation.journaltitlePUBLIC HEALTH NUTRITION-
dc.identifier.doi10.1017/S1368980016000550-
dc.identifier.wosidWOS:000384414900010-
dc.identifier.scopusid2-s2.0-84964055118-
dc.author.googleLamichhane, Dirga Kumar-
dc.author.googleLeem, Jong-Han-
dc.author.googleKim, Hwan-Cheol-
dc.author.googleLee, Ji-Young-
dc.author.googlePark, Myung-Sook-
dc.author.googleJung, Dal-Young-
dc.author.googleKo, Jung Keun-
dc.author.googleHa, Mina-
dc.author.googleKim, Yangho-
dc.author.googleHong, Yun-Chul-
dc.author.googleHa, Eun-Hee-
dc.contributor.scopusid하은희(7003615774)-
dc.date.modifydate20180329110124-
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의과대학 > 의학과 > Journal papers
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