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Identification of viral pathogens for lower respiratory tract infection in children at Seoul during autumn and winter seasons of the year of 2008-2009

Title
Identification of viral pathogens for lower respiratory tract infection in children at Seoul during autumn and winter seasons of the year of 2008-2009
Authors
Kim K.H.Kim J.H.Kang C.Kim K.S.Chung H.M.Kim D.S.
Ewha Authors
김경효
SCOPUS Author ID
김경효scopus
Issue Date
2010
Journal Title
Korean Journal of Pediatric Infectious Diseases
ISSN
1226-3923JCR Link
Citation
vol. 17, no. 1, pp. 49 - 55
Indexed
SCOPUS; KCI scopus
Abstract
Purpose: The Purposes of this study are to identify the circulating etiologic viruses of acute lower respiratory tract infection in children and to understand the relation with clinical diagnosis. Methods: We obtained a total of 418 nasopharyngeal aspirates from children admitted for their acute lower respiratory tract infections at three tertiary hospitals in Seoul from September 2008 to March 2009. We performed multiplex RT-PCR to identify 14 etiologic viruses and analyzed their emerging patterns and clinical features. Results: Average age of patients was 16.4 months old and the ratio of male to female was 1.36. Viruses were detected in 56.2% of a total of 418 samples. Respiratory syncytial virus (35%) was the most frequently detected and followed by human rhinovirus (22%), human bocavirus, adenovirus, human metapneumovirus, parainfluenza virus, influenza virus and human coronavirus. Co-infection reached 21.9 % of positive patients. Conclusion: When we manage the patients with acute lower respiratory infectious diseases, we should remind the role of various viral pathogens, which might be circulating by seasons and by local areas.
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의학전문대학원 > 의학과 > Journal papers
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