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Clinical comparisons of 0.5% and 0.375% levobupivacaine for ultrasound-guided axillary brachial plexus block with nerve stimulation

Title
Clinical comparisons of 0.5% and 0.375% levobupivacaine for ultrasound-guided axillary brachial plexus block with nerve stimulation
Authors
Kim W.Kim Y.J.Kim J.-H.Kim D.Y.Chung R.K.Kim C.H.Heo S.
Ewha Authors
김치효김종학정락경김동연김윤진
SCOPUS Author ID
김치효scopus; 김종학scopus; 정락경scopus; 김동연scopus; 김윤진scopus
Issue Date
2012
Journal Title
Korean Journal of Anesthesiology
ISSN
2005-6419JCR Link
Citation
vol. 62, no. 1, pp. 24 - 29
Indexed
SCOPUS; KCI scopus
Abstract
Background: In an axillary brachial plexus block (ABPB), where relatively large doses of local anesthetics are administered, levobupivacaine is preferred due to a greater margin of safety. However, the efficacy of levobupivacaine in ABPB has not been studied much. We performed a prospective, double-blinded study to compare the clinical effect of 0.375% levobupivacaine with 0.5% levobupivacaine for ultrasound (US)-guided ABPB with nerve stimulation. Methods: Forty patients undergoing elective upper limb surgery were randomized into two groups: Group I (0.375% levobupivacaine) and Group II (0.5% levobupivacaine). All four main terminal nerves of the brachial plexus were blocked separately with 7 ml of levobupivacaineusing US guidance with nerve stimulation according to study group. A blinded observer recorded the onset time for sensory and motor block, elapsed time to be ready for surgery, recovery time for sensory and motor block, quality of anesthesia, patient satisfaction and complications. Results: There were no significant differences in the time to find nerve locations, time to perform block and number of skin punctures between groups. Insufficient block was reported in one patient of Group I, but no failed block was reported in either group. There were no differences in the onset time for sensory and motor block, elapsed time to be ready for surgery, patient satisfaction and complications. Conclusions: 0.375% levobupivacaine produced adequate anesthesia for ABPB using US guidance with nerve stimulation, without any clinically significant differences compared to 0.5% levobupivacaine. © The Korean Society of Anesthesiologists, 2012.
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의학전문대학원 > 의학과 > Journal papers
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